2023年7月5日 · For grade II tumors, experts recommended adding CTV margins of 5 mm to GTVs in normal brain tissue, hyperostosis, around invaded bone, and along normal (unthickened) meninges and venous sinuses contacting the GTV.

As radical radiation therapy for non-small-cell lung cancer becomes increasingly precise following the development of techniques such as image-guided radiotherapy and intensity-modulated radiotherapy, how we define the clinical target volume (CTV) ...

2021年3月1日 · The gross tumor volume (GTV) is defined as the visible lesion on MRI; typically, this is the contrast-enhancing lesion. The clinical target volume (CTV) is defined as the volume of tissue that contains the GTV and any microscopic disease and potential paths of …

2022年5月5日 · The diffusive nature of HGGs implies that tumor cell invasion of normal tissue extends several centimeters away from the visible gross tumor volume (GTV). The standard methodology for clinical volume target (CTV) delineation is to apply a 2- to 3-cm margin around the GTV. However, tumor recurrence is extremely frequent.

Ten cases consisting of 5 glioblastomas and 5 grade II or III gliomas, including their respective gross tumor volume (GTV), clinical target volume (CTV), and OARs were each contoured by 6 experienced neuro-radiation oncologists from 5 international institutions.

2022年11月1日 · GTV is defined by T1 contrast-enhancing lesion, thickened meninges, and directly invaded bone. For IMRT, the CTV include: Grade I: No margin around the GTV. Grade II: Margin of 5mm to expand GTV in normal brain tissue, hyperostosis, along the unthickened meninges and venous sinuses if the GTV is coming into contact.

2022年11月1日 · GTV is defined by T1 contrast-enhancing lesion, thickened meninges, and directly invaded bone. For IMRT, the CTV include: Grade I: No margin around the GTV. Grade II: Margin of 5mm to expand GTV in normal brain tissue, hyperostosis, along the unthickened meninges and venous sinuses if the GTV is coming into contact.

2011年11月15日 · The consensus on GTV and CTV for preoperative radiotherapy of high-grade large extremity STS is available as web-based images and in a descriptive format through the RTOG. This is expected to improve target volume consistency and allow for rigorous evaluation of the benefits and risks of such treatm …

2021年6月7日 · In this study, we performed a consecutive macropathologic analysis to assess microscopic extension (ME) in high-grade glioma (HGG) to determine appropriate clinical target volume (CTV) margins for radiotherapy. The study included HGG patients with tumors located in non-functional areas, and supratotal resection was performed.

2024年10月11日 · The addition of weekly online MR-Linac (MRL) adaptive radiotherapy to treatment with temozolomide (Temodar) led to a significant reduction in clinical target volume (CTV) margins and limited...