Growth hormone receptor (GHR) is a transmembrane protein consisting of 620 amino acids. The receptor is part of the Type I cytokine receptor family of receptors. GHR exists in two forms as a full length membrane-bound receptor and as a soluble GH binding protein (GHBP).

The growth hormone receptor (GHR), although most well known for regulating growth, has many other important biological functions including regulating metabolism and controlling physiological processes related to the hepatobiliary, cardiovascular, …

2019年2月8日 · Human growth hormone (GH) is a classical pituitary endocrine hormone that is essential for normal postnatal growth and has pleiotropic effects across multiple...

2023年9月15日 · 生长激素受体（growth hormone receptor, GHR）跨膜蛋白质，广泛存在于人体内各种细胞中。 它主要负责介导生长激素（GH）在目标细胞上的生物学效应，调节细胞生长、增殖和分化等生理过程。

生长激素受体（英語： Growth hormone receptor)是一种由人类基因GHR 编码的蛋白质 [1] ，GHR的直系同源物 [2] 广泛存在于各种哺乳动物中。 此基因编码的蛋白是结合 生长激素 的跨膜受体。

The GHR gene provides instructions for making a protein called the growth hormone receptor. This receptor is embedded in the outer membrane of cells throughout the body and is most abundant in liver cells.

2018年3月16日 · In this Review, the authors chart the history of growth hormone, from discovery to clinical development and therapeutic approval, and discuss the emerging pathophysiology and treatment of its ...

2020年10月15日 · Growth hormone-releasing hormone (GHRH) regulates the secretion of growth hormone that virtually controls metabolism and growth of every tissue through its binding...

2024年12月25日 · GHR (Growth Hormone Receptor) is a Protein Coding gene. Diseases associated with GHR include Laron Syndrome and Growth Hormone Insensitivity, Partial. Among its related pathways are Endochondral ossification with …

The GHR signaling pathway plays important roles in growth, metabolism, cell cycle control, immunity, homeostatic processes, and chemoresistance via both the JAK/STAT and the SRC pathways. Dysregulation of GHR signaling is associated with various diseases and chronic conditions such as acromegaly, cancer, aging, metabolic disease, fibroses ...