Human milk oligosaccharides (HMOs) are an evolutionarily significant advantage bestowed by mothers for facilitating the development of the infant's gut microbiota. They can avoid absorption in the stomach and small intestine, reaching the colon successfully, where they engage in close interactions w …

Sep 17, 2024 · Breast milk contains viable bacteria, but there is no significant difference in MOM microbiota between NEC and controls. Integrative analysis between MOM microbiota, human milk oligosaccharides (HMOs), and the infant gut microbiota shows positive correlations only between Acinetobacter in the infant gut and Acinetobacter and Staphylococcus in MOM.

Human milk contains a number of nutritional and bioactive molecules including microorganisms that constitute the so-called “Human Milk Microbiota (HMM)”. Recent studies have shown that not only bacterial but also viral, fungal, and archaeal components are present in the HMM.

Sep 13, 2020 · Human milk oligosaccharides (HMOs) shape the gut microbiota in infants by selectively stimulating the growth of bifidobacteria. Here, we investigated the impact of HMOs on adult gut microbiota and gut barrier function using the Simulator of the Human Intestinal Microbial Ecosystem (SHIME^® …

Oct 1, 2021 · Human milk contains a complex nutritional and bioactive composition including microorganisms and oligosaccharides which would also contribute to the gut and immune system maturation. Despite the growing evidence, the factors contributing to milk microbes’ variations and the potential functions on the infant's gut are still uncovered.

Mar 1, 2013 · Human milk is a complex species-specific biological fluid adapted to satisfy the nutritional requirements of the rapidly growing infant; additionally, it educates the infant immune system and confers a certain degree of protection against pathogens [1].

Aug 31, 2023 · To investigate the potential for a HMO mixture reflecting the full complexity of human breast milk to modulate the adult gut microbiome, we conducted a clinical study in healthy adults to...

Apr 1, 2024 · In this study, we focused on human milk as the feeding method and specifically, the relationship between components of human milk, and the composition of the gut microbiome of infants exclusively fed human milk for the first 6 mo of life.

Aug 21, 2024 · Human milk oligosaccharides (HMOs) are an evolutionarily significant advantage bestowed by mothers for facilitating the development of the infant's gut microbiota. They can avoid absorption in the stomach and small intestine, reaching the colon successfully, where they engage in close interactions with gut microbes.

In addition to exceptionally nutritive and bioactive components, human milk encompasses a complex community of signature bacteria that helps establish infant gut microbiota, contributes to maturation of infant immune system, and competitively interferes with pathogens.