2024年12月25日 · GZMB (Granzyme B) is a Protein Coding gene. Diseases associated with GZMB include Stevens-Johnson Syndrome and Peripheral T-Cell Lymphoma. Among its …

2025年2月8日 · Title: A robust gene prognostic index composed of GZMB, IRF1, and TP63 can stratify the risk of two metastatic urothelial carcinoma cohorts based on immune checkpoint …

2021年1月12日 · GzmB mediates loss of hemidesmosomal proteins, type XVII collagen (COL17) and α6 integrin, in an EBA murine model. We next aimed to elucidate the mechanisms …

GZMs are a family of serine proteases that were originally identified in the cytotoxic granules of cytotoxic T and NK cells. The most-abundant and best-characterized members, GZMA and …

Human and murine Granzymes play important roles in immune responses, crucial for eliminating aberrant cells. GzmB, a serine protease initially identified in the granules of cytotoxic …

2022年11月9日 · Our study support the involvement of GzmB-expressing CD8+ T cells in the inflammatory response in patients with NMOSD and provide a potential biomarker for disease …

2022年5月2日 · The chemical design of activity-sensing reporters of granzyme B (GzmB) represents a potentially effective strategy for monitoring the cytotoxic activity of CD8+ T cells …

Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro. A robust gene prognostic index composed of GZMB, IRF1, and TP63 can stratify the …

2014年12月18日 · Granzyme B (GzmB) is a protease with a well-characterized intracellular role in targeted destruction of compromised cells by cytotoxic lymphocytes. However, GzmB also …

2024年12月10日 · Clinical resource with information about GZMB, Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo., and available tests. There are links to …