2017年4月10日 · Herein, we identify a novel Cyclophilin A (CypA) small molecule inhibitor (HL001) that induces non-small cell lung cancer (NSCLC) cell cycle arrest and apoptosis via …

NCI-H292细胞可以作为筛选模型，将人类亚基因入细胞来研究HBV及其自身基因在病毒性肝炎和肝癌发生中的作用。 NCI-H292细胞角蛋白、波形蛋白、黏液洋线，但神经丝三联蛋白阴性。

Differential constitutive activation of the epidermal growth factor receptor in non-small cell lung cancer cells bearing EGFR gene mutation and amplification. Signatures of mutation and …

2017年9月6日 · Using co-immunoprecipitation and correlation analyses, we found that O -GlcNAcylation of p53 under certain cellular contexts, i.e. high p53 activation, promotes its …

2022年12月17日 · In this study, we show that knockdown of BECN1 leads to p53 stabilization resulting in cellular senescence and that oncogenic Ras elevates nuclear Beclin 1 expression …

2018年2月13日 · In this paper we applied our upstream analysis algorithm to identify master regulators potentially responsible for dumping down the sensitivity of particular lung cancer cell …

2017年8月8日 · Just like the observation that p53 is down-regulated in lung cancer; p53 silencing enhances IDO1 expression in lung cancer cells. To determine whether deregulation of IDO1 is …

NCI-H292 是来源于人粘液表皮样肺癌细胞系，在 M-NSG 小鼠皮下接种后，能正常成瘤。

人肺癌细胞NCI-H292 [H292]说明书 于一名32 岁黑人女性。此细胞株源自肺粘液� �皮癌的淋巴结转移灶。 这个细胞系最初用化学合成培养基(HITES) 分离获得, 后期培养转换

2012年3月21日 · Erlotinib was shown to decrease phosphorylation of JAK2 and STAT-5 in EGFR-negative myelodysplastic syndrome (MDS) cell lines KG-1 [50] and erlotinib can disrupt …