gamma H2A.X (H2AX)靶点介绍及实验小贴士| Abcam中文官网
本网页介绍了gamma H2A.X (H2AX)蛋白的功能、表达、定位、异构体和翻译后修饰，以及WB和ICC实验中的注意事项、阳性对照和结果示例。gamma H2A.X (H2AX)是一种核小体组蛋白， …
H2AFX - Wikipedia
H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. An important phosphorylated form is γH2AX (S139), which forms when double-strand breaks appear.
In humans and other eukaryotes, the DNA is wrapped around histone octamers, consisting of core histones H2A, H2B, H3 and H4, to form chromatin. H2AX contributes to nucleosome-formation, chr…Wikipedia · CC-BY-SA 许可下的文字- 预计阅读时间：7 分钟
本文综述了H2AX磷酸化的生物学特征、检测方法和在DNA损伤和修复中的作用,以及在生殖相关细胞中的应用。H2AX磷酸化是指组蛋白H2AX在其C端第139位丝氨酸上发生磷酸化修饰形 …
DNA损伤检测—你中意哪一个？ - 知乎 - 知乎专栏
γH2AX: a sensitive molecular marker of DNA damage and repair
2010年2月4日 · Phosphorylation of the Ser-139 residue of the histone variant H2AX, forming γH2AX, is an early cellular response to the induction of DNA double-strand breaks.
- 作者: Mah Lj, El-Osta A, El-Osta A, Karagiannis Tc, Karagiannis Tc
- Publish Year: 2010
H2AX: A key player in DNA damage response and a
2024年6月1日 · This review article explains the molecular dynamics of H2AX, a histone variant that is phosphorylated at Ser-139 (γH2AX) in response to DNA double-strand breaks. It …
H2AX Gene - GeneCards | H2AX Protein | H2AX Antibody
2024年12月25日 · H2AX is a histone variant that replaces conventional H2A in a subset of nucleosomes and is involved in DNA repair and cell cycle checkpoint. Learn about its aliases, disorders, domains, pathways, products, transcripts, …
H2AX: functional roles and potential applications - PMC
H2AX is a histone H2A variant that constitutes 2–25% of mammalian histone H2A depending on the organism and cell type (Redon et al. 2002; Rogakou et al. 1998).
H2AX Phosphorylation: Its Role in DNA Damage …
Development of an antibody, that is specific to γH2AX, made it possible to detect H2AX phosphorylation and thus detection of DNA damage and repair in situ in individual cells. The presence of γ H2AX in chromatin can be detected shortly …
CNS前沿文献追踪：DNA损伤修复过程中的γH2AX - 健 …
2020年4月8日 · 本文介绍了一篇nature子刊的研究，利用SIM超分辨、ChIP-seq等技术，探讨了DNA损伤修复过程中γH2AX蛋白在染色质上的分布和功能。文章发现γH2AX先在常染色质上，后在异染色质上，与DNA压缩程度和修复进度有 …
- 某些结果已被删除
