2006年6月30日 · H 2 O 2 production has been studied most extensively in neutrophils. These immune cells defend a host against infections by engulfing and killing foreign microorganisms.

To determine if H 2 O 2 is a suitable apoptosis inducer for a given cell type, we measured cytochemical and genetic indices of apoptosis and necroptosis under a range of H 2 O 2 …

2013年8月1日 · One ROS that has been identified as a major second messenger in redox signaling is hydrogen peroxide (H 2 O 2). This small, membrane-permeable oxidant is …

Hydrogen peroxide (H2O2) is an oxidizing agent that induces cellular damage at inappropriate concentrations and gives rise to an arrest during cell cycle progression, causing cell death. …

2010年11月1日 · Using C6 glioma cells in this study we investigated in detail how exposure time and cell concentration affect the cytotoxic potency of H 2 O 2 in vitro. Median cytotoxic …

The studies reported here investigate H2O2-induced cell death in more detail. Our data suggest that exposure of cultured cortical neurons to H2O2 can induce apoptotic cell death within 3 h, …

Understanding how to regulate the actions of H2O2 in T cells will allow for the creation of novel ways to improve the treatment of inflammatory diseases. The current study presents baseline …

Hydrogen peroxide (H 2 O 2) is an important intra- and extra-cellular signaling molecule that can determine cell fate. At low concentrations, H 2 O 2 plays roles in proliferation, immunity, and …

2007年4月13日 · Here, we will discuss the molecular mechanisms by which hydrogen peroxide is sensed and the increasing evidence that antioxidant enzymes play multiple, key roles as …

2010年2月19日 · Mammalian cells use hydrogen peroxide (H2O2) not only to kill invading pathogens, but also as a signaling modulator. Woo et al. (2010) now show that the local …