H2ZX Analysis - BlackRock Global Funds - Nutrition Fund
2025年3月10日 · Performance charts for BlackRock Global Funds - Nutrition Fund (H2ZX) including intraday, historical and comparison charts, technical analysis and trend lines.
γH2AX是DNA 损伤尤其是DNA 双链断裂(DNA double-strand breaks,DSB) 或DNA修复的标志物,已经被应用到医学相关领域,如放射性DNA 损伤的检测、癌症的辅助诊断以及预后监测。 此 …
gamma H2A.X (H2AX)靶点介绍及实验小贴士| Abcam中文官网
gamma H2A.X为磷酸化蛋白，建议在裂解液中加入复合蛋白酶抑制剂和复合磷酸酶抑制剂，以防止蛋白在提取时降解和去磷酸化。 gamma H2A.X 蛋白预测分子量为15 kDa，建议根据小分 …
γH2AX: a sensitive molecular marker of DNA damage and repair
2010年2月4日 · Phosphorylation of the Ser-139 residue of the histone variant H2AX, forming γH2AX, is an early cellular response to the induction of DNA double-strand breaks. Detection …
Phospho-Histone H2A.X (Ser139) Antibody | Cell Signaling …
Histone H2A.X is a variant histone that represents approximately 10% of the total H2A histone proteins in normal human fibroblasts (1). H2A.X is required for checkpoint-mediated cell cycle …
Histone H2AX phosphorylation: a marker for DNA damage
Because phosphorylation of H2AX at Ser 139 (γ-H2AX) is abundant, fast, and correlates well with each DSB, it is the most sensitive marker that can be used to examine the DNA damage …
H2AX promotes replication fork degradation and ... - Nature
2024年5月24日 · Histone H2AX plays a key role in DNA damage signalling in the surrounding regions of DNA double-strand breaks (DSBs). In response to DNA damage, H2AX becomes …
DNA damage signalling histone H2AX is required for tumour growth
2024年2月24日 · Histone γH2AX has a critical role in the cellular DNA repair pathway cascade and contributes to genomic stability. However, the role of γH2AX in the ontology of cancer is …
Considerations for the Use of the DNA Damage ... - Wiley Online …
DNA double-strand breaks are known to be the most lethal kind of DNA damage as they cause genomic instability. Visualization and quantification of these breaks are possible via staining of …
H2AX: functional roles and potential applications - PMC
H2AX is a histone H2A variant that constitutes 2–25% of mammalian histone H2A depending on the organism and cell type (Redon et al. 2002; Rogakou et al. 1998).
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