Histone H3K23-specific acetylation by MORF is coupled to H3K14 ... - Nature
2019年10月17日 · Acetylation of histone H3K23 has emerged as an essential posttranslational modification associated with cancer and learning and memory impairment, yet our …
MORF 的组蛋白 H3K23 特异性乙酰化与 H3K14 酰化偶联。,Nature …
2019年10月17日 · 在这里，我们将天然 morf 复合物鉴定为组蛋白 h3k23 特异性乙酰转移酶，并阐明其作用机制。 催化 MORF 亚基的乙酰转移酶功能受到 MORF 的 DPF 结构域 (MORFDPF) …
EIN2-dependent regulation of acetylation of histone H3K14 …
2016年10月3日 · In this study, we demonstrate that the acetylation of lysine 14 of histone H3 (H3K14Ac) and non-canonical acetylation of lysine 23 of histone H3 (H3K23Ac) are up …
Histone acetyltransferase CBP-related H3K23 acetylation …
2018年11月20日 · H3K23ac, catalysed by the acetyltransferases dCBP, contributes to Drosophila learning, likely by controlling the expression of specific genes. This is a novel epigenetic …
De novo methylation of histone H3K23 by the methyltransferases …
2022年11月21日 · Here, we report that the canonical histone H3K9 methyltransferases EHMT1/GLP and EHMT2/G9a are capable of catalyzing methylation of histone H3 lysine 23 …
Uhrf1-dependent H3K23 ubiquitylation couples maintenance …
2013年9月8日 · Here we show that Uhrf1-dependent histone H3 ubiquitylation has a prerequisite role in the maintenance DNA methylation. Using Xenopus egg extracts, we successfully …
Histone H3K18 & H3K23 acetylation directs establishment of MLL …
2024年8月1日 · We show that the contributions of H3 tail acetylation to H3K4 methylation by MLL1 are highly variable, with H3K18 and H3K23 acetylation exhibiting robust stimulatory …
<br>组蛋白H3K18和H3K23乙酰化指导建立MLL介导的H3K4 ... - X …
2024年7月1日 · 我们表明 h3 尾乙酰化对 mll1 的 h3k4 甲基化的贡献是高度可变的，h3k18 和 h3k23 乙酰化表现出强大的刺激作用，并且这延伸到相关的 h3k4 甲基转移酶复合物 mll4。
Two H3K23 histone methyltransferases, SET-32 and SET-21, …
2024年11月6日 · In this study we identified SET-21 as a novel H3K23 HMT. By taking combined genetic, biochemical, imaging, and genomic approaches, we found that SET-21 functions …
Methylation of histone H3K23 blocks DNA damage in pericentric ...
2014年8月26日 · Mass spectrometric sequencing of micronuclear H3 identified H3K23 trimethylation (H3K23me3), a previously uncharacterized PTM. H3K23me3 became …