[Hepatitis B virus (HBV) mutation in enhancer I (HBV Enh I)/X …
Objective: To investigate the hepatitis B virus (HBV) mutation in the Enhancer I (HBV Enh I)/X-promoter and to analysis the relationship between chronic HBV-related disease spectrum.
乙型肝炎病毒增强子的结构和调控研究
Lee et al研究发现, 通过人肝细胞Enh I的E因子的AP1位点, 人乳头瘤病毒16型EP6蛋白(HPV-16 E6)和HBV X蛋白对HBV前基因组有反式激活作用. 提示HPV-16可以增强HBV和其他启动子含 …
Stronger enhancer II/core promoter activities of hepatitis B virus ...
2016年7月27日 · HBV DNA replication is driven by pregenomic RNA, which is controlled by core promoter (CP) and further augmented by enhancer I (ENI) and enhancer II (ENII). DNA …
Genetic diversity in enhancer II region of HBV genotype D and its ...
2022年1月4日 · The HBV genome contains two transcriptional enhancer (Enh) regions i.e. Enh-I and Enh-II, which are important for viral replication. The Enh-II, located in nt 1636–1741, …
Enhancer I Predominance in Hepatitis B Virus Gene Expression
Our data provides strong evidence for the role of EnhI in regulating global and temporal HBV gene expression. Hepatitis B virus (HBV) is the prototype of the hepadnaviridae, a family of small …
乙型肝炎病毒增强子Ⅰ/X基因启动子变异与HBV慢性感染疾病谱的 …
摘要. 目的 探讨乙型肝炎病毒增强子Ⅰ (HBV Enh Ⅰ)/X基因启动子变异与乙型肝炎病毒慢性化感染疾病谱的关系.方法 随机收集275例HBV感染,(
Genetic diversity in enhancer II region of HBV genotype D and its ...
2022年1月4日 · This study was designed to characterize the enhancer-II (Enh-II) region of X gene in HBV positive patients to assess the association of such mutations with CH, LC, and HCC. …
HBV T1719G mutation reduced HBV replication through mutant Enh …
Our results showed that the T1719G mutation impaired viral replication efficacy compared with the wild type both by reducing Enh II activity and binding capacity of HNF3β with Enh II. And such …
Genetic diversity in enhancer II region of HBV genotype D and its ...
2022年1月4日 · This study was designed to characterize the enhancer-II (Enh-II) region of X gene in HBV positive patients to assess the association of such mutations with CH, LC, and HCC.
Temporal acquisition of sequential mutations in the enhancer II …
2010年9月28日 · To investigate the roles of mutations in enhancer II (Enh II) and basal core promoter (BCP) of hepatitis B virus (HBV) in hepatocellular carcinoma (HCC), we determined …