Dilated vs. Hypertrophic Cardiomyopathy - HealthCentral
2024年5月30日 · Both dilated and hypertrophic cardiomyopathy restrict the pumping of blood in the body. A key difference between these types of cardiomyopathy is whether the ventricle …
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy
2022年6月22日 · Compared with NF hearts, DCM and HCM hearts showed a statistically credible decrease in cardiomyocytes and increases in vascular smooth muscle cells (VSMCs) and …
Nature｜单细胞核测序技术揭示心肌病转录图谱 - 腾讯网
2023年1月9日 · 扩张型心肌病（Dilated cardiomyopathy, DCM）和肥厚型心肌病（Hypertrophic cardiomyopathy, HCM）都是心衰的病因，二者至终末期均可发展为心衰，带来严重的公共健康 …
Shared genetic pathways contribute to risk of hypertrophic and …
2021年1月25日 · We show strong genetic correlations between LV traits and cardiomyopathies, with opposing effects in HCM and DCM. Two-sample Mendelian randomization supports a …
肥厚型心肌病的基因学和临床诊断现状与鉴别 - 知乎
肥厚型心肌病(hypertrophic cardiomyopathy，HCM)是一类最常见的单基因常染色体显性遗传性心肌病，也是青少年运动性猝死的最常见病因。 HCM以不明原因的心室对称性或非对称性肥厚 …
SHaRe – SHaRe Project
The goal of SHaRe, a first-of-its-kind effort, is to advance the understanding of Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM), and Arrhythmogenic …
Hypertrophic, Dilated, and Arrhythmogenic Cardiomyopathy: …
In the present review, we focus on three cardiomyopathies: dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), and arrhythmogenic cardiomyopathy (ACM). Herein we …
Evidence-Based Assessment of Genes in Dilated Cardiomyopathy
2021年5月5日 · The major cardiomyopathies, diseases of the myocardium, have clinically been classified as hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and …
The genetics of dilated cardiomyopathy - PMC - PubMed …
Dilated cardiomyopathy (DCM) is characterized by left ventricular dilatation and impaired systolic function and is a leading cause of heart failure. DCM is considered idiopathic if no other …
临床综述：心肌病十年研究进展 - 丁香园
2014年10月5日 · 心肌间质和局灶性纤维化是hcm的标志，纤维化导致hcm患者舒张和收缩功能受损。目前hcm间质纤维化的确切分子机制尚不清楚，较为统一的假设是发育生物学假设。