Her physical examination was remarkable for only sclera icterus and mild tenderness on palpation in the right lower quadrant. Investigations revealed marked hyperbilirubinemia and transaminitis, with other serological and radiological studies unremarkable and a hepatitis A, B and C panel negative 3 weeks before presentation.

2023年3月26日 · First diagnosed in 1989, the hepatitis C virus (HCV) is a significant public health problem affecting 58 million people worldwide. The percentage of people who are seropositive for anti-HCV antibodies worldwide is estimated to have increased from …

2024年9月18日 · Cutaneous manifestations seen in the setting of liver cirrhosis includes icterus, pruritus, spider angiomas, palmar erythema, xanthomas, pigmentary changes, nutritional deficiencies and hair & nail changes.

Here we report a 75-year-old Japanese female with chronic hepatitis C (genotype 2a) who developed HCVr after the administration of prednisolone for interstitial pneumonia. She experienced alanine aminotransferase (ALT) flare with icterus, but after the tapering of prednisolone and a liver supporting therapy, levels of HCV RNA and ALT were ...

The buildup of bilirubin in the bloodstream leads to jaundice or icterus, which is a yellow coloring of the skin and sclera (of note, scleral icterus can be seen when the bilirubin level exceeds 1.5 to 3 mg/dL). Note that only some patients with hepatitis are jaundiced because only some patients develop cholestasis.

Moreover, genotype 3 was significantly associated with icterus. A ROC curve analysis revealed that the best cut-off points for serum levels of aspartate aminotransferase (AST), ALT, and alkaline phosphatase (ALP) were >31, >34, and ≤246 IU/L, respectively.

She had icterus and hepatomegalia. In laboratory tests, alanine aminotransferase level was 504 U/L, aspartate aminotransferase level was 388 U/L, and anti-HCV and HCV-RNA tests produced positive findings. She was treated with interferon alfa-2a for a 1-year period.

2019年1月13日 · On physical exam, scleral icterus is appreciated in an uncomfortable appearing man. Abdominal exam is notable for tenderness to palpation in the right upper quadrant with mild hepatomegaly. Laboratory testing is notable for elevated aspartate and alanine aminotransferases and HCV RNA and anti-HCV antibody levels.

2023年7月7日 · During acute HCV infection, symptoms may appear similar to those of HBV infection. In up to 80% of cases, however, the patients are asymptomatic and do not develop icterus. [1, 18] The...

2017年3月1日 · Yellow discoloration of the eyes is termed “scleral icterus” and results from the accumulation of bilirubin in the ocular and periocular or periorbital tissues. Fig. 1. A: Bilateral periorbital arteriovenous hemangiomas and significant jaundice of periocular structures including eyelid skin, conjunctiva, and sclera in an advanced cirrhosis patient.