HDAC11 - Wikipedia
Histone deacetylase 11 is a 39kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. [5] [6] It is the only …
组蛋白去乙酰化酶11 (histone deacetylases 11, HDAC11) 是IV 类HDAC 的唯一成员，能够催化组蛋白和非 组蛋白赖氨酸残基去乙酰化并具有去脂酰化活性。 HDAC11 与免疫细胞的成熟、分 …
HDAC11 Gene - GeneCards | HDA11 Protein | HDA11 Antibody
2024年12月25日 · HDAC11 (Histone Deacetylase 11) is a Protein Coding gene. Diseases associated with HDAC11 include Mature T-Cell And Nk-Cell Lymphoma and Peripheral T-Cell …
HDAC11: a multifaceted histone deacetylase with proficient …
The histone deacetylases (HDACs) family of enzymes possess deacylase activity for histone and nonhistone proteins; HDAC11 is the latest discovered HDAC and the only member of class IV. …
一文带你了解组蛋白去乙酰化酶（HDAC） - 知乎专栏
hdac8和hdac11则优先水解非乙酰酰基赖氨酸底物，hdac10则是一种多胺去乙酰化酶。 HDAC催化机制 乙酰赖氨酸底物位于一个由疏水残基围绕的狭窄通道中，其中酪氨酸残基通过构象翻转 …
HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase …
2022年3月12日 · This study provided evidence that HDAC11 is highly expressed in the aortic intima of HFD-fed ApoE −/− mice and HDAC11 knockdown significantly suppressed pyroptosis …
聚焦药靶：HDAC抑制剂的最新研究进展 - 健康界
2021年9月6日 · HDAC（histonedeacetylases），中文全称叫做组蛋白脱乙酰酶，是组蛋白修饰过程中一类重要的酶，催化并调控组蛋白去乙酰化。 目前在人体中已经发现18种HDAC，分别 …
HDAC11, an emerging therapeutic target for metabolic disorders
2022年10月20日 · In this review, we summarize the recent progress on the role and mechanism of HDAC11 in the regulation of metabolic disorders, with the focus on its regulation on …
Hdac11 histone deacetylase 11 [ (house mouse)] - National Center …
2025年2月8日 · HDAC11 is a novel regulator of fatty acid oxidative metabolism in skeletal muscle. HDAC11 regulates expression of C/EBPbeta and immunosuppressive molecules in myeloid …
HDAC11: A novel target for improved cancer therapy - PubMed
2023年9月3日 · Histone deacetylase 11 (HDAC11) is a unique member of the histone deacetylase family that plays an important role in the regulation of gene expression and …