Heart failure with midrange ejection fraction (HFmrEF) is a new category of heart failure (HF), inbetween HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF). Previous studies were mainly conducted in HFrEF patients having a left ventricle ejection fraction (LVEF) lower than 35-40%.

2018年1月1日 · Heart failure has recently undergone major changes: while heart failure with reduced ejection fraction or HFrEF is declining due to effective revascularization of patients with acute coronary syndromes, 1–3 the prevalence and incidence of heart failure with preserved ejection fraction or HFpEF, mainly characterized by diastolic dysfunction, 4,5 ...

2021年9月6日 · Heart failure (HF) with mildly reduced ejection fraction (EF) (HFmrEF) has been extensively studied, generally using an EF of 40–49%, and accounts for up to 25% of patients with...

HFrEF 射血分数降低的心衰 (HFrEF)，LVEF<40%。 诊断标准： ①心衰的症状/体征； ②LEVF 40%~49%； ③利钠肽升高+（左心室肥厚、左心房扩大、心脏舒张功能异常）。 注：利钠 …

Heart failure (HF) with borderline or mid-range ejection fraction (HFmEF; 40% ≤EF <50%), the previously neglected “middle child of HF” (1), is increasingly receiving attention along with its famous older sibling, HF with reduced EF (HFrEF; EF <40%), and the favored baby of the HF family, HF with preserved EF (HFpEF; EF ≥50%).

Traditionally, patients with heart failure (HF) are divided according to ejection fraction (EF) threshold more or <50%. In 2016, the ESC guidelines introduced a new subgroup of HF patients including those subjects with EF ranging between 40 …

2023年12月4日 · dapa-hf和deliver的荟萃分析结果 总结 总体而言，根据射血分数，心力衰竭可分为HFrEF、HFmrEF与HFpEF，此外2022年AHA/ACC/HFSA 指南又新增HFimpEF，强调射血分数的动态演变过程。

2017年11月6日 · The following are summary points to remember from this review about features of heart failure with mid-range ejection fraction (HFmrEF) and how they compare with the more well-studied HF groups:

The introduction of heart failure (HF) with mid-range ejection fraction (HFmrEF) as a distinct phenotype has achieved its aim of stimulating research into the underlying characteristics, pathophysiology and treatment of HF patients with left ventricular ejection fraction of 40–49 %.

2016 ESC指南根据LVEF将心衰分为射血分数降低的心衰（HFrEF，LVEF<40%）、射血分数中间范围型心衰（HF with mid-range EF，HFmrEF）和射血分数保留的心衰（HFpEF，LVEF≥50%）三类，其中HFmrEF的LVEF范围是40％～49％。