Human herpesvirus 6 (HHV-6) is the common collective name for human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B). These closely related viruses are two of the nine known herpesviruses that have humans as their primary host. [1]HHV-6A and HHV-6B are double-stranded DNA viruses within the Betaherpesvirinae subfamily and of …

2023年8月8日 · Human herpesvirus 6 (HHV-6) was initially discovered in blood lymphocytes of adults with lymphoproliferative diseases or AIDS and was labeled human B-lymphotropic virus. Further research identified HHV-6 in CD4+ lymphocytes and as a member of the herpesviruses. As it was the sixth herpesvirus isolated, it was then subsequently renamed human herpesvirus 6. Typical of a herpes virus, HHV-6 has ...

在性病医院临床上将与人类有关的疱疹病毒称为人类疱疹病毒（Human herpes virus,HHV）。球形直径为120~150nm，dsDNA，衣壳呈二十面体对称，外复一层厚薄不匀的被膜，最外层为典型的脂质双层包膜，上有突起。HSV基因组可编码100多种多肽，已知至少有近十种系病毒的晚期蛋白，与病毒感染和破坏细胞密切 ...

1996年2月27日 · Human herpesvirus 6(HHV-6) is a human pathogen of emerging clinical significance. HHV-6 was first isolated from patients with lymphoproliferative disorders in 1986 (Salahuddin et al., 1986). HHV-6 isolates are classified into two groups as variants A(HHV-6A) and variant B(HHV-6B) (Schirmer et al., 1991. The two variants are closely related but show consistent differences in biological ...

Initially designated HBLV, for human B-lymphotropic virus, HHV-6 was isolated fortuitously in 1986 from interleukin 2-stimulated peripheral blood mononuclear cells (PBMCs) of patients with AIDS or lymphoproliferative disorders .The PBMC cultures exhibited an unusual cytopathic effect characterized by enlarged balloonlike cells.

Human Herpesvirus 6 (HHV-6) is a set of two closely related herpes viruses known as HHV-6A and HHV-6B. HHV-6B infects approximately 70% of children by the age of three and often results in fever, diarrhea, sometimes with a rash known as roseola.

Human herpesvirus (HHV) 6 is a β-herpes, DNA virus. This virus shows closest homology with cytomegalovirus and HHV-7. Infection usually occurs in infants 6 to 24 months of age, and primary infection may result in roseola. HHV-6 infection in infants is the commonest cause of fever-induced seizures. Infection in adults is seen primarily in immunocompromised hosts with solid organ transplants or ...

Human herpesvirus 6 (HHV-6) is a betaherpesvirus that is closely related to human cytomegalovirus. It was discovered in 1986, and HHV-6 literature has expanded considerably in the past 10 years. We here present an up-to-date and complete overview of ...

1.婴幼儿感染 HHV-6感染通常无症状， 原发感染 的婴幼儿或免疫缺陷的病人可出现明显症状。 多数原发感染发生在6个月～2岁的儿童，重症者出现 婴儿玫瑰疹 (即第六病)，常突然发作，伴有高热(39～40℃)，持续3～5天后热度骤降，在24h内体温降至正常。 热退时出现淡红色斑疹或斑丘疹，通常先发生于 ...

A beta herpesvirus (like cytomegalovirus [CMV], human herpesvirus 7 [HHV-7], and human herpesvirus 8 [HHV-8]), HHV-6 is characterized by two strains (A and B), considered distinct from each other. [1, 8, 10, 11, 12] HHV-6B is the predominant strain of the virus documented in seroprevalence studies in the United States and Japan.HHV-6A disease has been documented to cause disease in only ...