Hereditary haemorrhagic telangiectasia (HHT) is an inherited genetic disorder that affects the blood vessels. It's also known as Osler-Weber-Rendu syndrome. People with HHT have some …

We have one mission that drives everything we do to find a cure for HHT disease, a genetic blood vessel disorder that affects 1 in 5,000 people - 90% of whom are undiagnosed.

Our HHT and PAVM services care for and treat patients with hereditary haemorrhagic telangiectasia (HHT, also known as Osler Weber Rendu syndrome) and/or pulmonary arteriovenous malformations (PAVMs). Hammersmith Hospital has had a centre for specialist treatment of these conditions since 1983.

2021年12月10日 · Hereditary hemorrhagic telangiectasia (HHT), the second most common inherited bleeding disorder, is associated with the development of malformed blood vessels.

WHAT IS HHT? • HHT is caused by a single change in one of 4 genes, and usually runs in families. • HHT affects more than 10,000 people in the UK- though most are not diagnosed. • HHT usually (but not always) causes nosebleeds that if regular, lead to anaemia. • People with HHT may have obvious blood spots- but usually they are difficult ...

2023年5月16日 · Hereditary haemorrhagic telangiectasia (HHT) is also known as Osler-Weber-Rendu syndrome. The condition is characterised by vascular dysplasia leading to telangiectasia. Epistaxis and gastrointestinal bleeding are frequent complications of mucosal involvement.

2020年9月8日 · The Guidelines were developed by an international panel of HHT experts and patients, providing new evidence-based consensus recommendations in six priority topic areas: Epistaxis, Gastrointestinal Bleeding, Anemia & Iron Deficiency, Liver VMs, Pediatric Care, Pregnancy & Delivery.

Results: The 2010 UK point prevalence for HHT was 1.06/10 000 person years (95% CI 0.95 to 1.17) or 1 in 9400 individuals. The diagnosed prevalence of HHT was significantly higher in women compared with men (adjusted prevalence rate ratio (PRR) 1.53, 95% CI 1.24 to 1.88) and in those from the most affluent socioeconomic group compared with the ...

HHT stands for H ereditary emorrhagic T elangiectasia. It is a rare hereditary disorder that causes abnormal connections, called arteriovenous malformations (AVMs), to develop between arteries and veins. The most common locations affected are the nose, lungs, brain and liver. HHT affects 1 in 5000 people worldwide.

2000年6月26日 · Hereditary hemorrhagic telangiectasia (HHT) is characterized by the presence of multiple arteriovenous malformations (AVMs) that lack intervening capillaries and result in direct connections between arteries and veins. The most common clinical manifestation is spontaneous and recurrent nosebleeds (epistaxis) beginning on average at age 12 years.