
Nonspecific Interstitial Pneumonia in a Patient with HIV
2018年12月10日 · We present a case of newly diagnosed HIV heralded by acute NSIP which resolved with corticosteroid therapy alone and was later complicated by PJP, suggesting that HIV screening be implemented for all new cases of undifferentiated NSIP.
In one study on 351 HIV-positive patients with pneumonitis, NSIP was the most common histologic diagnosis in patients without PCP3. Because treatment and prognosis of PCP and NSIP are different, it is important to differentiate these entities.
Nonspecific Interstitial Pneumonia - StatPearls - NCBI Bookshelf
2023年8月14日 · NSIP is chronic interstitial pneumonia with the homogeneous appearance of interstitial fibrosis and inflammation. It is nonspecific as it lacks the histopathological features of the other subtypes of the IIP. NSIP typically has bilateral lung involvement and may have a predisposition for the lower lobes.[1][2][3][4][5]
Nonspecific interstitial pneumonia (NSIP) - EMCrit Project
2023年11月16日 · HIV has been associated with NSIP, but this is less common with modern therapies for HIV. idiopathic NSIP. The existence of truly idiopathic NSIP is debatable. Most of these patients likely have some underlying autoimmune process, which may not have yet fully manifested itself.
非特异性间质性肺炎病理诊断中国专家共识(草案) - 中华结核和 …
NSIP(纤维化型)患者胸部CT示双肺对称性,以双肺下叶和胸膜下为主的网格阴影、磨玻璃密度影,有牵拉性支气管扩张,胸膜下无蜂窝肺(图2,3);图4为该患者两年后肺移植右侧全肺切除标本,切面示全肺体积缩小,质地较硬,呈弥漫性灰白色实变,灰白和灰 ...
The etiology of nonspecific interstitial pneumonitis in acquired ...
2007年1月1日 · The role of HIV in pathogenesis of NSIP is not known. Our retrospective study showed detailed history and close follow-up may be helpful to reveal the etiology of the NSIP. Cocaine abuse, disseminated M. avium complex infection, CMV pneumonitis, and immune reconstitution syndrome showed to be considered a potential cause of NSIP in patients ...
非特异性间质性肺炎的临床、组织学和CT表现 - iikx
NSIP 是一种慢性的 ILD (间质性肺疾病),表现为由炎症或纤维化引起的肺泡壁均匀增厚。 NSIP 患者的肺活检与其他类型的间质性肺炎是相矛盾的,但足以不同而独立划分为一类。 临床特点. NSIP 预后优于 UIP 。 NISP 的症状也较轻微,包括数月内逐渐加重的咳嗽和呼吸困难,体重减轻,及衰弱。 多大数患者在确诊时年龄为 40~ 50 岁。 无性别差异。 吸烟可能是罹患疾病的危险因素。 组织学表现. NSIP 的组织学亚型是连续的,从细胞病变到细胞病变混合纤维化,依赖于肺 …
非特异性间质性肺炎病理诊断中国专家共识(草案)
2018年12月17日 · NSIP是间质性肺炎的一种类型,临床主要表现为渐进性呼吸困难和咳嗽,高分辨率CT (high resolution CT, HRCT)显示双下肺及胸膜下分布为主的对称性磨玻璃影,网状阴影和牵拉性支气管或细支气管扩张,很少或无蜂窝形成;病理学特点表现为肺间质不同程度的炎症和纤维化,病变时相一致。 可继发于感染(如人免疫缺陷病毒)、自身免疫性疾病、药物性肺损伤和有机粉尘的吸入等,称为继发性NSIP。 原因不明者称之为INSIP,为独立的疾病类型,属于IIPs …
Nonspecific interstitial pneumonitis mimicking Pneumocystis carinii ...
Among 67 patients without Pneumocystis, nonspecific interstitial pneumonitis (NSIP) was the most common histologic diagnosis (n = 16). Tissue sections from patients with NSIP were tested by in situ hybridization for Epstein-Barr virus, cytomegalovirus (CMV), and HIV; sections were also tested with the polymerase chain reaction (PCR) for HIV env ...
Noninfectious and Nonneoplastic Conditions Associated with …
Lymphoid interstitial pneumonitis (LIP) and nonspecific interstitial pneumonia (NSIP) have been reported in both HIV-infected children and adults, and NSIP is more common than LIP in HIV-infected patients. At present, there is no consensus on the pathogenesis of LIP and NSIP in HIV.