Herpes simplex virus type 2 (HSV-2) and syphilis are associated with HIV infection. The purpose of this review is to summarize the advances in the relationship of HSV-2 and syphilis with HIV, highlighting intervention trials to prevent HIV acquisition and transmission.

2009年8月17日 · Genital herpes, caused by the herpes simplex virus type 2 (HSV-2), is one of the most common sexually transmitted infections worldwide. It is also associated with a 2- to 3-fold increased risk for HIV infection. Some people infected with HSV-2 suffer from recurring sores and breaks in genital skin.

HIV and herpes simplex virus type 2 (HSV-2) infections cause a substantial global disease burden and are epidemiologically correlated. Two previous systematic reviews of the association between HSV-2 and HIV found evidence that HSV-2 infection increases the risk of HIV acquisition, but these reviews are now more than a decade old. Methods

2013年10月28日 · Despite an observation that HSV-2 activity is associated with increased HIV viral load, definitive evidence linking HSV-2 seropositivity to accelerated HIV disease progression is lacking. The attenuating effects of acyclovir on HIV disease progression observed in recent trials may result both from d …

Among viral STIs, only herpes simplex virus-2 (HSV-2) has been studied extensively for its role in HIV acquisition, transmission, and pathogenesis. However, the role of human herpesviruses (HHVs) as asymptomatic viral STIs (other than HSV-2) has not been given due importance despite their high seroprevalence in HIV-infected individuals[ 8 ] and ...

Herpes simplex virus type 2 (HSV-2) is one of the most prevalent sexually transmitted infections worldwide and is the cause of most genital herpes. 1 The NHANES III survey showed that 16.2% of individuals 14 years and older were HSV-2 seropositive. 2 The public-health significance of HSV-2 infection is tremendous, with an estimated annual ...

2014年9月11日 · Here, we review the diseases produced by herpes simplex viruses, the factors that modulate HSV-2 infection, the relationship between HSV-2 and HIV and novel therapeutic and prophylactic microbicides/antivirals under development to prevent infection and pathological outcomes produced by this virus.

2024年9月10日 · Genital herpes is a common sexually transmitted virus infection that is found worldwide. Genital herpes can be caused by either herpes simplex virus type 2 (HSV-2) or type 1 (HSV-1); most recurrences are caused HSV-2 as HSV-1 does not recur often in the genital area .

Infections with human herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are common. Among persons aged 14 to 49 years in the United States, the HSV-1 seroprevalence is 47.8%, and the HSV-2

2013年10月28日 · Herpes simplex virus type 2 (HSV-2) is a common co-infection among HIV-infected adults that is hypothesized to accelerate HIV disease progression. We searched Medline, EMBASE, relevant conference proceedings (2006–12) and bibliographies of identified studies without language restriction for cohort studies examining the impact of HSV-2 on ...