
Vpu protein - Wikipedia
Vpu is an accessory protein that in HIV is encoded by the vpu gene. Vpu stands for "Viral Protein U". The Vpu protein acts in the degradation of CD4 in the endoplasmic reticulum and in the …
Role of Viral Protein U (Vpu) in HIV-1 Infection and Pathogenesis
2021年7月27日 · Vpu is an HIV-1 accessory protein generated from Env / Vpu encoded bicistronic mRNA and localized in cytosolic and membrane regions of cells capable of being infected by …
Vpu Protein: The Viroporin Encoded by HIV-1 - PMC
Viral protein U (Vpu) is a lentiviral viroporin encoded by human immunodeficiency virus type 1 (HIV-1) and some simian immunodeficiency virus (SIV) strains. This small protein of 81 amino …
Cell Rep:揭示HIV-1逃避宿主机体免疫系统攻击的新机制 - 知乎
近日,一篇发表在国际杂志 Cell Reports上题为“HIV-1 Vpu restricts Fc-mediated effector functions in vivo”的研究报告中,来自蒙特利尔大学等机构的科学家们通过研究发现,用来研究非中和性 …
HIV-1 Vpu protein forms stable oligomers in aqueous solution via …
2023年9月6日 · We report our findings on the assembly of the HIV-1 protein Vpu into soluble oligomers. Vpu is a key HIV-1 protein. It has been considered exclusively a single-pass …
hiv-i vpu蛋白的结构与功能研究进展 - 道客巴巴
2016年6月4日 · Vpu 蛋白通过多种机制促进 HIV-1 病毒的释放,包括在细胞膜上形成选择性阳离子通道来增强通透性;诱导细胞表面病毒受体 CD4 分子的降解;拮抗宿主抗病毒因子骨髓基质 …
Various plus unique: Viral protein U as a plurifunctional protein for ...
2017年2月28日 · Viral protein U (Vpu) is a unique protein encoded by human immunodeficiency virus type 1 (HIV-1) and related lentiviruses, playing multiple roles in viral replication and …
Role of HIV-1 Vpu protein for virus spread and pathogenesis
2008年7月1日 · Vpu is an accessory viral protein almost unique to HIV-1 among primate immunodeficiency viruses, and has two major functions: degradation of the CD4 molecule in …
HIV-1 Vpu – An ion channel in search of a job - PMC
Vpu is a small membrane protein encoded by HIV-1 and some SIV isolates. The protein is best known for its ability to degrade CD4 and to enhance the release of progeny virions from …
The HIV-1 Vpu protein: a multifunctional enhancer of viral particle ...
2003年9月1日 · This review focuses on presenting our current knowledge of the HIV-1-specific Vpu protein and its essential role in regulating viral particle release, viral load and expression …