这就要依靠 长末端重复序列 (LTR)来发挥作用。 HIV基因组两端的长末端重复序列的排列方式是相同的，从3’端到5’端依次有三个片段区域，分别是U3区、R区和U5区。 但在vRNA中，LTR是 …

The initial transcription of the HIV-1 genome is controlled by the 5′ long terminal repeat (LTR) and is dependent upon host cell transcription factors binding to an array of DNA cis -regulatory …

HIV-1 LTR driven reporter vector that retains complete LTRs, tat, and rev, but has a frameshift mutation in env, an ngfr reporter gene in place of nef, and gfp in place of gag, pol, vif, and vpr

2018年1月1日 · Transcription of HIV-1 is controlled by a promoter located within the 5′ long terminal repeat (5′-LTR) of the integrated provirus. The HIV-1 5′-LTR is a long, promiscuous …

HIV-1病毒有着非常复杂的表达调控系统，序列分析显示HIV-1结构基因的表 达主要通过HIV-1 5’LTR的U3和R区的启动元件以及pol基因的内部启动子来控制 [1]。

2014年5月16日 · HIV-1 gene expression is driven by the long terminal repeat (LTR), which contains many binding sites shown to interact with an array of host and viral factors.

Our data highly suggest that 2-LTRc can serve as substrates for HIV-1 IN and, thus, may serve as a new source for the retroviral genome integration. This leads us to reconsider the different …

2024年5月2日 · The HIV-1 provirus mainly consists of internal coding region flanked by 1 long terminal repeats (LTRs) at each terminus. The LTRs play important roles in HIV-1 reverse …

6 天之前 · Results In our approach, we constructed a 1-LTR circular form of HIV in order to study its expression in isolation from the other forms; we derived a linear genomic HIV DNA lacking …

2022年5月18日 · In this review, we examine the HIV RNA in the form of un-translated terminal region (UTR), the viral DNA in the form of long terminal repeat (LTR), and the immunity of …