In this system, an "HLA" is used in conjunction with a letter, *, and a four-or-more-digit number (e.g., HLA-B*08:01, A*68:01, A*24:02:01N N=Null) to designate a specific allele at a given HLA locus.

The final set of numbers (HLA-A*02:101:01:01) is used to designate a single or multiple nucleotide polymorphism in a non-coding region of the gene. The final aspect of HLA naming is a letter (HLA-A*02:101:01:01 L). There are six letters, each with a different meaning.

2019年9月20日 · Each HLA allele name has a unique number corresponding to up to four sets of digits separated by colons. The length of the allele designation is dependent on the sequence of the allele and that of its nearest relative.

2021年8月11日 · HLA为前缀，A表示基因，使用星号*与4个数字区域进行分割。 被冒号“：”分隔的四个数字区域分别标示以下内容： 一些特殊标记： 表示肽链结合区（HLA class I：exon2 …

The human leukocyte antigen (HLA) system is one of the most crucial host factors influencing disease progression in bacterial and viral infections. This review provides the basic concepts of the structure and function of HLA molecules in humans. ...

The human leukocyte antigens (HLA) encoded by genes within the major histocompatibility complex display an impressive degree of polymorphism. This variability is apparently maintained in human populations through the need to successfully display a ...

one or more letters following the HLA. Individual alleles of each locus, and the corresponding specifici-ties, will be designated by numbers following the locus symbols. Provisionally identified specificities will, as before, carry the additional letter W(w), which will now be inserted between the locus letter(s

2023年2月27日 · High-resolution HLA typing is routinely performed to provide HLA matching in hematopoietic stem cell transplantation to prevent allograft rejection and graft-versus-host disease.

Curriculum HLA for the Rest of Us Short Answer: H Biology & Function of HLA: ha oes HLA stand f r pa HLA Structure and Naming: l

This reference guide describes recommended procedures for sequencing HLA Class I and Class II genes for producing fully-phased, unambiguous, allele-level information on the Sequel®, Sequel II and Sequel IIe Systems (Sequel Systems). HLA genes can be amplified using commercial assays (e.g., GenDx) or customers’ own custom assays.