HLA-B35 - Wikipedia
HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products. [ 1 ] B35 is one of the largest B serotype groups, it currently has 97 known …
HLA-B*35:01 Allele Is a Potential Biomarker for Predicting
In the independent replication study and combined analyses, a logistic regression model confirmed that HLA-B*35:01 is a high-risk allele of PM-DILI (PM-DILI versus other DILI, OR, …
Generation of the HLA-B35, -B5, -B16, and B15 groups of
HLA-B is the most polymorphic of the major histocompatibility complex classical class I loci. This polymorphism is mainly in exons 2 and 3, which code for the molecule’s α1 and α2 domains …
The HLA-B*35 allele modulates ER stress, inflammation and …
Our study demonstrates that HLA-B*35 contributes to the dysregulated expression of selected ER stress, inflammation and proliferation related genes in lcSSc patient PBMCs, as well as …
Molecular analysis of HLA-B35 alleles and their relationship
The HLA-B35 serotype is one of the largest allelic groups of HLA class I molecules and includes four isotypes. Of the four, the B35 variant isoform is relatively rare and is the most acidic form. …
HLA-B35 - an overview | ScienceDirect Topics
HLA-B35 is a specific type of HLA class I gene that has been found to show excess transmission in patients with pauciarticular-onset juvenile idiopathic arthritis. AI generated definition based …
Molecular insights into the HLA‐B35 molecules' classification ...
Human leukocyte antigen (HLA) class I molecules have been shown to influence the immune response to HIV infection and acquired immunodeficiency syndrome progression. …
新进展！欧阳冬生教授团队研究揭示HLA-B*35:01介导何首乌肝损 …
2024年7月25日 · 近日，都正生物“复杂基质样本生物分析湖南省重点实验室”主任欧阳冬生教授团队的最新研究成果《HLA-B*35:01-mediated activation of emodin-specific T cells contributes to …
Full-length sequences of 4 HLA-B*35 alleles, B*35:02:01:01, B ... - PubMed
1 Immunogenetic Laboratory, Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China. Full-length sequences of 4 alleles of HLA-B*35 gene …
都正学术 | HLA-B*35:01等位基因是人类潜在的能预测何首乌肝损 …
2020年4月20日 · 该项研究表明：HLA-B*35:01是何首乌肝损伤的风险等位基因，具有预测何首乌肝损伤的潜在价值。 同时证实 何首乌仅对极少数特定人群有肝损伤风险，对绝大对数人群是 …