HLA-B57 (B57) is an HLA-B serotype. B57 is a split antigen from the B17 broad antigen, the sister serotype being B58. [2] The serotype identifies the more common HLA-B*57 gene products. …

HIV control is strongly associated with the expression of human leukocyte antigen (HLA) alleles in HICs. From the HIV protective HLAs described, HLA-B57 is the most frequent in HIC patients. …

2024年10月6日 · After establishing a link between the HLA-B*57:01 allele and abacavir, monitoring for the allele and hypersensitive response became routine in antiretroviral therapy, …

2018年11月8日 · Here we explore the impact of micropolymorphism on peptide antigen presentation by three closely related HLA molecules, HLA-B*57:01, HLA-B*57:03 and HLA …

2015年9月1日 · The HLA-B gene plays an important role in how the immune system recognizes and responds to pathogens, and mediates hypersensitivity reactions. HLA-B*57:01 has been …

HLA types associated with slow progression of the infection such as HLA-B27 and HLA-B57 stimulate more effective immune responses compared with those that confer increased …

The HLA-B gene provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. …

2018年11月8日 · Immunophenotypic differences between closely related human leukocyte antigen (HLA) alleles have been associated with divergent clinical outcomes in infection, …

HLA-B*57 and HLA-C*06 were significantly higher in the patients indicating risk for psoriasis. HLA-B*57 was high in patients with history of erythroderma, hospital internment, systemic …

2008年2月7日 · Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective …