羟基频哪酮视黄酸酯（HPR）是一种新型的类视黄醇，研究显示它刺激性更小，但效力很高，是一种安全、有效的抗衰老和抗痤疮成分，因而受到国内外化妆品企业的青睐。

Retinol + HPR Ceramide Capsules Rapid Skin Renewing Serum visibly reduces wrinkles in 7 days 1 without irritation 2 and leaves skin with improved texture and tone. Gentle formula can be used day and night and is 10X more potent than pure retinol 3 for fast results.

Our Retinol + HPR Ceramide Serum Capsules formula is 10x more potent than pure retinol & gentle on skin to use day & night to visibly reduce wrinkles with 180 pieces.

科学家把HPR添加在细胞培养物中，然后通过检测RNA的水平来观察基因表达的变化。 结果发现HPR的表达模式跟维A酸的一致，也就是说HPR不需像视黄醇那样，经过层层转化才能起作用，自身就能跟受体结合，改变细胞基因的表达。

2023年3月29日 · A popular choice is HPR— also known as Granactive Retinoid. Let's talk about what HPR is, how it works, find out if HPR is more gentle than retinol, and how to pick the right anti-aging products for your skin.

Twist and squeeze out serum and apply to face and neck<br> <br>SKIN TYPES <br>Suitable for all skin types, even sensitive skin<br> <br>USE WITH <br>For even more youth-restoring results, use with Retinol + HPR Ceramide Rapid Skin Renewing Water Cream<br>

2024年9月9日 · 将其用于98位痤疮患者，连续12周，评估对痤疮的效果，皮损平均减少了40.8% ，仅15.3%的患者出现了局部的不适，研究认为含有 HPR和视黄醇、木瓜蛋白酶的配方可安全有效地用于痤疮护理[3]。

HPR具有天然的视黄酸活性，可直接与视黄酸受体结合，发挥功效。 且刺激性低于视黄酸和大多数视黄醇衍生物，是温和、安全、有效的抗衰老类视黄酸。

2024年2月7日 · RETINOL + HPR – visibly smooths lines & wrinkles, improves skin cell renewal without irritation. POWER PEPTIDES – help to visibly smooth stubborn lines and wrinkles and support natural collagen production. PHYTOCERAMIDES – plant-based ceramide, which maintain and repair the skin’s barrier function and increase moisturisation.