2024年12月25日 · HRK (Harakiri, BCL2 Interacting Protein) is a Protein Coding gene. Diseases associated with HRK include Cycloplegia and Trichuriasis. Among its related pathways are …

HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles …

2009年7月30日 · Here we show the data on the 5′-CpG methylation status, loss of heterozygosity on 12q13.1 and its association with HRK expression in human malignancies, including …

2019年2月8日 · Harakiri (HRK) is a BH3-only protein of the Bcl-2 family and regulates apoptosis by interfering with anti-apoptotic Bcl-2 and Bcl-xL proteins. While its function is mainly...

Here we show the data on the 50-CpG methylation status, loss of heterozygosity on 12q13.1 and its association with HRK expression in human malignancies, including prostate cancers, …

Here we show the data on the 5'-CpG methylation status, loss of heterozygosity on 12q13.1 and its association with HRK expression in human malignancies, including prostate cancers, …

gene perturbations changing expression of HRK gene from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. LOCATE Predicted Protein Localization Annotations

This gene encodes a member of the Bcl-2 protein family. Members of this family are involved in activating or inhibiting Apoptosis. The encoded protein localizes to intracellular membranes. …

2024年3月5日 · This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular …

HRK is a target of epigenetic inactivation in colorectal and gastric cancer; Hrk is involved in the induction of apoptosis in RGCs after optic nerve transection. The interaction between HRK …