Human serum albumin (HSA) is a highly water-soluble globular monomeric plasma protein with a relative molecular weight of 67 KDa, consisting of 585 amino acid residues, one sulfhydryl group and 17 disulfide bridges.

Serum albumin is the most abundant protein in the blood and cerebrospinal fluid and plays a fundamental role in the distribution of essential transition metal ions in the human body. Human serum albumin (HSA) is an important physiological transporter of the essential metal ions Cu 2 +, and Zn 2 + in the bloodstream.

Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multidomain macromolecule that represents the main determinant of plasma oncotic pressure and the principal modulator of fluid distribution between body compartments.

Human serum albumin (HSA) is a protein that transports neutral and acid ligands in the organism. Depending on the environment’s pH conditions, HSA can take one of the five isomeric forms that change its conformation. HSA can form aggregates resembling those in vitro formed from amyloid at physiological pH (neutral and acidic).

Human serum albumin (HSA) is the most abundant protein in plasma, contributing actively to oncotic pressure maintenance and fluid distribution between body compartments. HSA acts as the main carrier of fatty acids, recognizes metal ions, affects ...

2019年2月15日 · Human serum albumin (HSA) is an opulent, non-glycosylated, most versatile carrier protein in plasma possessing multiple functions. HSA has the ability to interact with a variety of ligands, including exogenous pharmacological drugs. HSA has multiple binding sites located in different subdomains and which are responsible for binding of ligands.

2023年1月1日 · Human Serum Albumin (HSA) excels in drug accommodation, making it a versatile drug carrier with vast therapeutic potential. This review summarizes HSA's structural diversity and explores genetic, biomedical, and allosteric aspects in drug delivery.

What is the HSA protein? HSA is a complex protein composed of 609 amino acids, with a molecular weight of 66.5 kDa and a maximum circulatory half-life of up to 19 days in human. Structurally, its secondary formation includes 67% α-helix, …

Human serum albumin (HSA) is the most abundant plasma protein in the human body with a plasma concentration of 0.6mM. HSA plays an important role in drug transport and metabolism. Enzymatic activity of HSA on different substrates or drugs has been studied and documented.

2016年11月2日 · Human serum albumin (HSA) is a multifunctional protein exclusively synthesized by liver hepatocytes and continuously secreted into the circulation. Here, it is the most abundant protein and comprises 60–65 % of total plasma protein.