The HSQC (Heteronuclear Single Quantum Coherence) experiment is used to determine proton-carbon single bond correlations, where the protons lie along the observed F2 (X) axis and the carbons are along the F1 (Y) axis. An edited HSQC spectrum of …

2014年4月7日 · HMBC is one of the most often used and vital NMR experiments for the structure elucidation of organic and inorganic molecules. We have developed a new, high sensitivity NMR pulse sequence that overcomes the typical 2,3 J CH limitation of HMBC by extending the visualization of long-range correlation data to 4-, 5-, and even 6-bond long-range n J ...

1：1h-nmr谱 核磁氢谱提供了化合物分子中有无活泼氢，各种活泼氢的分配及相互位置关系等。 该谱图表明,对氨基苯甲酸乙酷分子中有五种不等性的氢(没有考虑芳环上氢的区别)。

Just as COSY spectra show which protons are coupled to each other, HMBC (and the related HMQC) give information about the relative relationships between protons and carbons in a structure. In an HMQC spectrum, a 13 C spectrum is displayed on one axis and a 1 H spectrum is displayed on the other axis.

Gained Information: The Heteronuclear Multiple Bond Correlation (HMBC) NMR experiment is a proton-detected 2D experiment that shows you 1H / 13C multiple-bond connectivity. You will see your 1H spectrum as your direct F2 axis and your 13C chemical shifts as your indirect F1 axis.

The heteronuclear single quantum coherence or heteronuclear single quantum correlation experiment, normally abbreviated as HSQC, is used frequently in NMR spectroscopy of organic molecules and is of particular significance in the field of protein NMR. The experiment was first described by Geoffrey Bodenhausen and D. J. Ruben in 1980. [1]

2022年10月1日 · In this paper, we present two new three-module NORD experiments, NORD {HMBC}-{HSQC-TOCSY}-{TOCSY} and NORD {HMBC}-{2BOB}-{TOCSY}, each delivering four spectra covering the needs of most small-molecule NMR analyses.

2011年1月8日 · 2D HMBC (Heteronuclear Multiple Bond Correlation) experiment correlates chemical shifts of two types of nuclei separated from each other with two or more chemical bonds. This is an improvement of the old COLOC experiment.

2015年1月1日 · Special focus will be made on novel HSQC schemes including concepts such as fast NMR and pure shift NMR. In addition, reference to improved J -compensated HSQC sequences will be made, discussing the effects of the intensity and phase signal modulation dependence with respect to 1 J (CH) and/or J (HH) which are generated during INEPT periods.

核磁共振技术（nmr）作为结构鉴定最权威的方法，深受化学家们的衷爱。 其中， 1H NMR，13C NMR，DEPT135°，1H-1H COSY，HSQC和HMBC是实验室最常见的谱图，仅通过氢谱和碳谱，我们通常可以很好地确证简单化合物的结…