Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of HSP. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed. However, all four elements of this tetrad are not required for diagnosis.

2021年9月21日 · Henoch-Schonlein purpura is an inflammation of the small blood vessels of the skin, joints, bowels and kidneys. When blood vessels get inflamed, they can bleed into the skin, causing a reddish-purple rash (purpura). The most striking feature of this form of vasculitis is a purplish rash, typically on the lower legs and buttocks.

2020年8月15日 · Henoch-Schönlein purpura, now called immunoglobulin A (IgA) vasculitis, is a systemic, immune complex–mediated, small-vessel leukocytoclastic vasculitis characterized by...

Subcutaneous edema, which is a common finding in HSP, particularly appears in the hands, ankles, and feet while edema occurring in other locations is uncommon (2,3). Face, scalp, preno-scrotal and labial edema have been reported in a number of patients (3,6–9). Facial edema is predominantly seen in children younger than 2 years .

2024年7月15日 · Henoch-Schönlein purpura (HSP) is a disease that inflames small blood vessels. The inflammation causes blood vessels in the skin, intestines, kidneys, and joints to start...

The clinical manifestations of HSP can take days to weeks to fully develop and may vary in order of appearance; Purpura occurs in all patients but is the presenting complaint in only 75% of cases; Recent upper respiratory tract infection is present in 50% of HSP cases, commonly viral or Group A streptococcus infections

Henoch–Schönlein purpura (HSP) is a small vessel vasculitis which is characterized by palpable purpura, arthritis, abdominal pain, and nephritis . Although subcutaneous oedema of dependent areas has often been reported, scalp oedema in older children with HSP is extremely rare.

2024年10月28日 · Immunoglobulin A vasculitis (IgAV; formerly called Henoch-Schönlein purpura [HSP]) , is the most common form of systemic vasculitis in children, with an incidence range of 3 to 27 per 100,000 . Ninety percent of cases occur in the pediatric age group. In contrast to many other forms of systemic vasculitis, IgAV is typically self-limited.

Henoch–Schönlein purpura (HSP) is a form of leukocytoclastic or small-vessel vasculitis, most often observed in children. It is sometimes called anaphylactoid purpura. HSP results from inflammation of the small blood vessels in the skin and various other tissues within the body. HSP generally affects children, but it may also occur in adult ...

2020年10月21日 · Henoch-Schoenlein purpura (HSP) is an IgA-mediated small-vessel vasculitis caused by deposition of immune complexes within vessel walls >75% of patients with HSP are less than 10 years old, with a peak between ages 4 and 6 years