Henoch-Schönlein Purpura (HSP) is the commonest small vessel vasculitis of childhood with an estimated incidence of 14–20.4/100 000. The vasculitis (IgA-dominant immune deposits) affects small vessels and typically involves skin, gut and glomeruli and is associated with arthralgias or arthritis. HSP typically presents with the triad of:

Henoch-Schonlein purpura (IgA vasculitis) is a condition characterized by a widespread necrotizing vasculitis of arterioles and small capillaries. Classically, children aged 3 to 8 years …

Abbreviation: HSP Classical triad of non-thrombocytopenic palpable purpura , abdominal pain , arthritis Most common vasculitis in childhood (usually 2-11 yr)

Written by expert consultants and clinical scientists currently practising in the UK, the BSH Guidelines provide up-to-date evidence-based guidance on the diagnosis and treatment of haematological diseases. Patients with accelerated or blast phase myeloproliferative neoplasms have a dismal prognosis.

过敏性紫癜又称亨-舒综合症（Henoch-Schonlein purpura,HSP），是一种较常见的微血管 变态反应性出血性疾病。 病因有感染、食物过敏、 药物过敏 、 花粉 、昆虫 咬伤 等所致的过敏等，但过敏原因往往难以确定。

2020年10月21日 · Henoch-Schoenlein purpura (HSP) is an IgA-mediated small-vessel vasculitis caused by deposition of immune complexes within vessel walls >75% of patients with HSP are less than 10 years old, with a peak between ages 4 and 6 years; White and Asian males are more commonly affected

2014年5月26日 · HSP（手机规格，Head-Set-Profile） 这是最常用的配置，为当前流行支持蓝牙耳机与移动电话使用，提供手机与耳机之间通信所需的基本功能。 连接和配置好后，耳机可以作为远程设备的音频输入和输出接口。

研究人员正在探索使用hsp抑制剂作为一种潜在的癌症治疗策略。 热休克蛋白（如gp96）可以增强患者自身对于癌症的免疫力。 gp96与其特定受体，如抗原呈递细胞上的CD91相互作用后，抗原向主要组织相容性复合体I类交叉呈递，并增加辅助刺激分子的释放，如B7。

Use FVIIa, high dose FFP or IVIg. - Beta-lactam antibiotics. Usually resolves on cessation of drug. Notes - 80% in plasma, 20% in platelets. Produced in hepatocytes. - Levels rise in pregnancy. Notes - 99% circulates as inactive zymogen. - Weak lab/clinical correlation. - 65% asymptomatic. Spontaneous bleeding is uncommon.

Haem oxygenase-1 (HO-1) is a stress protein and a rate-limiting enzyme in haem degradation, generating ferrous iron, carbon monoxide and bile pigme...