Heat shock transcription factor 1 (HSF1) is the main regulator of the stress response that triggers the transcription of several genes encoding heat shock proteins (Hsps). Hsps act as molecular …

2024年12月4日 · Evidence from mammalian models indicates that HS significantly impairs ovarian function, disrupting hormone profiles, reducing ovarian size and weight, altering …

Our studies confirm that, even in absence of any stress, HSF1 regulates Hsp70.1 in oocytes and early embryos. Our data emphasize the role of maternal and paternal HSFs in the …

2020年4月1日 · Heat stress reduces oocyte competence, thereby causing lower fertility in animals. Chronic and acute heat stresses cause extensive morphological damage in animals, …

In order to understand whether different genes or different promoter elements are involved in the two types of control, several genomic clones coding for Xenopus heat-shock proteins, hsp 70 …

2024年8月1日 · Heat stress significantly impacts the normal development of mammalian oocytes and embryos, leading to substantial economic losses in animal agriculture. This review …

2021年12月19日 · Transcription of heat shock proteins (HSPs) is a key element to facilitate reestablishment of cellular homeostasis. Unlike somatic cells, cellular mechanisms by which …

Using the Xenopus oocyte model system, our laboratory has shown that HSP90 is present in immune complexes with both active and inactive HSF1 and further that disruption of HSP90 in …

oocytes are noted germinal vesicle (GV) oocytes from the name given to their voluminous nucleus. Around ovulation, GV oocytes resume meiosis and progress until the metaphase …

Heat stress reduces oocyte competence, thereby causing lower fertility in animals. Chronic and acute heat stresses cause extensive morphological damage in animals, but few reports have …