Henoch-Schonlein purpura (HSP) is an immune-mediated systemic vasculitis generally found in children. The standard manifestations of HSP are palpable purpura, arthritis, abdominal pain, and renal complications. Although less common, there are significant urological manifestations associated with HSP.

A first episode of HSP, in the absence of significant renal disease, usually resolves within 4 weeks. Rash is often the last symptom to remit; Joint pain usually resolves spontaneously within 72 hours; Uncomplicated abdominal pain usually resolves spontaneously within 24-48 hours

2024年3月12日 · Henoch-Schönlein purpura (HSP), also known as anaphylactoid purpura, causes small blood vessels in your body, including those in the skin, stomach and kidneys, to become swollen and leak. One of the most obvious and common signs of this disease is a rash on the skin that looks like purple or red dots.

Renal manifestations in IGAV/HSP. Renal involvement occurs in a variable proportion (20–60%) of children suffering from IGAV/HSP [2, 7, 8]. Vast majority of children with IGAV/HSP (97%) develop features of renal involvement within 6 months of disease onset, but sometimes HSPN may occur later [7, 9–11]. The renal disease spectrum ranges from ...

We retrospectively reviewed demographic factors, clinical features, and laboratory data and identified the risk factors for renal involvement in children with HSP. Recent studies have reported relationships between laboratory and clinical findings and …

2014年4月15日 · This review summarizes important aspects of the epidemiology and the clinical course of HSP-nephritis (HSPN), including renal biopsy findings and their potential prognostic significance. Prevailing concepts on etiology and pathophysiology as well as different treatment approaches are discussed.

1998年6月1日 · This study is the first report in which the relationship between the progression of renal involvement in Henoch-Schönlein purpura (HSP) and various factors was evaluated using a multivariate analysis. Sixty-five (33.5%) of 194 patients with HSP developed renal involvement from three days to 17 months after the onset of the disease.

2005年12月1日 · The risk of developing renal impairment when a patient had only isolated hematuria or proteinuria was very low (1.6%). If a patient developed nephritis or nephrotic syndrome, the risk of renal impairment increased to 19.5%, with females 2.5 times more likely to be in the renal impairment group.

Most patients with renal involvement make a good recovery with long term morbidity being <5%. HSP nephritis accounts for < 3% of end stage renal failure (2). Treatment of HSP nephritis is debatable. In severe renal involvement cases discuss with UHW Paediatric nephrologists because of potential long term consequences.

3 天之前 · Renal manifestations in HSP nephritis vary from transient urinary abnormalities to progressive glomerular disease. The most common pattern involves isolated hematuria with or without mild proteinuria, often resolving without long-term damage. However, some patients develop persistent proteinuria and declining kidney function, necessitating ...