Science | 发现全新的决定内质网应激下细胞命运的调控因子 - 知乎
于是作者通过测量 Xbp1s （由IRE1介导的剪接Xbp1转录本）和Hspa5（ATF6目标基因）的总体种群水平表达来监测IRE1和ATF6的活性。研究人员验证了Xbp1s和Hspa5在Tm处理开始后的12 …
HSPA5 Gene - GeneCards | BIP Protein | BIP Antibody
2024年12月25日 · The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. This protein localizes to the lumen of the endoplasmic reticulum (ER) where it …
HSPA5 Gene encoding Hsp70 chaperone BiP in the
2017年6月30日 · The HSPA5 gene encodes the binding immunoglobulin protein (BiP), an Hsp70 family chaperone localized in the ER lumen. As a highly conserved molecular chaperone, BiP …
Identification of heat shock protein family A member 5 (HSPA5
2023年5月8日 · Heat shock protein family A (Hsp70) member 5 (HSPA5) is an endoplasmic reticulum chaperone, which regulates cell metabolism, particularly lipid metabolism. While …
HSPA5 Promotes the Proliferation, Metastasis and Regulates …
HSPA5 is also known as GRP78 or BIP, and it localizes to the lumen of the endoplasmic reticulum (ER). HSPA5 is involved in protein folding and assembly as a molecular chaperone of HSP70 …
HSPA5 heat shock protein family A (Hsp70) member 5 [ (human)]
The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. This protein localizes to the lumen of the endoplasmic reticulum (ER) where it operates as a typical …
HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic …
2017年6月30日 · The HSPA5 gene encodes the binding immunoglobulin protein (BiP), an Hsp70 family chaperone localized in the ER lumen. As a highly conserved molecular chaperone, BiP …
EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic …
2023年9月11日 · Here, we report that E1A binding protein P300 (EP300) acetyltransferase promotes ferroptosis in human pancreatic ductal adenocarcinoma (PDAC) cells via the …
热休克蛋白家族 A (Hsp70) 成员 5（HSPA5）基因 | MCE
热休克蛋白家族 a (hsp70) 成员 5： 该基因编码的蛋白质是热休克蛋白 70 (hsp70) 家族的成员。这种蛋白质定位于内质网 (er) 的腔，在那里它作为典型的 hsp70 伴侣蛋白参与 er 中蛋白质的折 …
ER Stress-Related Genes EIF2AK3, HSPA5, and DDIT3 ... - PubMed
2022年7月14日 · Objective: This study aimed to evaluate the associations between endoplasmic reticulum (ER) stress-related genes EIF2AK3/PERK, HSPA5/GRP78, and DDIT3/CHOP …