The 2D HSQC (Heteronuclear Single-Quantum Correlation) experiment permits to obtain a 2D heteronuclear chemical shift correlation map between directly-bonded 1H and X-heteronuclei (commonly, 13C and 15N) .

2023年2月11日 · In an HSQC spectrum, a 13 C or heteroatom spectrum is displayed on one axis and a 1 H spectrum is displayed on the other axis. Cross-peaks show which proton is attached to which carbon or heteroatom. The purpose of a HSQC is to determine which protons are coupled to what other specific carbon or heteroatom in the molecule through bonds.

2019年7月24日 · Heteronuclear Single Quantum Coherence (HSQC) A protein is make-up of a series of amino acid monomers. Although there are 19 different amino acids each with a distinct side chain, the protein backbone is an invariable pattern of NH-C-CO as shown in Figure 5.

The 2D HSQC (Heteronuclear Single-Quantum Correlation) experiment permits to obtain a 2D heteronuclear chemical shift correlation map between directly-bonded 1H and X-heteronuclei (commonly, 13C and 15N) .

The heteronuclear single quantum coherence or heteronuclear single quantum correlation experiment, normally abbreviated as HSQC, is used frequently in NMR spectroscopy of organic molecules and is of particular significance in the field of protein NMR. The experiment was first described by Geoffrey Bodenhausen and D. J. Ruben in 1980. [1]

The HSQC (Heteronuclear Single Quantum Coherence) experiment is used to determine proton-carbon single bond correlations, where the protons lie along the observed F2 (X) axis and the carbons are along the F1 (Y) axis. An edited HSQC spectrum of …

How does the HSQC work? The HSQC is a poster-child for building block sequences. The red part of the above pulse sequence diagram is an optional TANGO (see last month’s topic), it varies only in the phase of the last (red) S pulse and with the gradient thereafter.

多糖的结构解析中，hsqc二维核磁是开展糖苷键连接确认的基础谱图。 从有机物的HSQC解谱而言，代表的相连接的C-H相关，比如乙醇CH3-CH2-OH，其HSQC谱图中，甲基的质子和甲基碳有相交叉的信号，而亚甲基质子和亚甲基…

The 2D HSQC-NOESY experiment is an hybrid inverse experiment consisting of an initial HSQC pulse train followed by a NOESY building block. In the first step, magnetization is transferred from the X nucleus (13C or 15N) to the directly-bonded proton nuclei via 1 J(CH).

We propose a design, micro fabrication process, and nuclear magnetic resonance based evaluation, of a magnetic field gradient chip. The uni-axial linear z-gradient coil design was computed by a...