Identifying the common rate limiting steps of the infection may help the development of antiviral agents that are capable of preventing the virus entry into host cell. In this review we describe the major features of HSV entry that have contributed to the wide susceptibility of cells to HSV infection.
了解详细信息：Identifying the common rate limiting steps of the infection may help the development of antiviral agents that are capable of preventing the virus entry into host cell. In this review we describe the major features of HSV entry that have contributed to the wide susceptibility of cells to HSV infection.
virologyj.biomedcentral.com/articles/10.1186/1743 …HSV-1 is capable of using multiple modes of spread to transfer from infected to uninfected cells and increase the number of its progeny virions. Elucidating the mechanism of viral dissemination and subsequent entry into neighboring cells is important to understand the infection process.
pmc.ncbi.nlm.nih.gov/articles/PMC4822157/Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and show an extraordinary ability to bind more than one receptor on the ...
pmc.ncbi.nlm.nih.gov/articles/PMC7848091/To study the multimodal response of single human cells to herpes simplex virus type 1 (HSV-1) infection, we mapped high-dimensional viral and cellular state spaces throughout the...
www.nature.com/articles/s41467-023-40148-6Our study provides insights into early stages of HSV-1 infection and serves as a general blueprint for the investigation of heterogeneous cell states in virus infection.
www.nature.com/articles/s41467-019-12894-zHerpes simplex virus infects most cell types in vitro: clues to its ...
2011年10月26日 · Identifying the common rate limiting steps of the infection may help the development of antiviral agents that are capable of preventing the virus entry into host cell. In this review we describe the major features of HSV entry that have contributed to the wide …
Cell entry mechanisms of HSV: what we have learned in …
HSV-1 is capable of using multiple modes of spread to transfer from infected to uninfected cells and increase the number of its progeny virions. Elucidating the mechanism of viral dissemination and subsequent entry into neighboring cells …
Herpes Simplex Virus Cell Entry Mechanisms: An Update
Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and show …
Cellular state landscape and herpes simplex virus type 1 infection ...
2023年7月27日 · To study the multimodal response of single human cells to herpes simplex virus type 1 (HSV-1) infection, we mapped high-dimensional viral and cellular state spaces …
Single-cell RNA-sequencing of herpes simplex virus 1-infected …
2019年10月25日 · Our study provides insights into early stages of HSV-1 infection and serves as a general blueprint for the investigation of heterogeneous cell states in virus infection.
Herpes simplex virus infects most cell types in vitro: clues
2011年10月26日 · Herpes simplex virus (HSV) type-1 and type-2 have evolved numerous strategies to infect a wide range of hosts and cell types. The result is a very successful …
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The HSV-1 mechanisms of cell-to-cell spread and …
2018年5月9日 · All herpesviruses have mechanisms for passing through cell junctions, which exclude neutralizing antibodies and offer a clear path to neighboring, uninfected cells. In the case of herpes simplex virus type 1 (HSV …
Caspase-8 is required for HSV-1-induced apoptosis and promotes …
2022年11月24日 · Regulated cell death (RCD) plays an important role in the progression of viral replication and particle release in cells infected by herpes simplex virus-1 (HSV-1).
The HSV-1 mechanisms of cell-to-cell spread and fusion are
2018年5月9日 · All herpesviruses have mechanisms for passing through cell junctions, which exclude neutralizing antibodies and offer a clear path to neighboring, uninfected cells. In the …
Single-cell herpes simplex virus type 1 infection of …
2024年2月28日 · This study applies drop-based microfluidics to investigate the dynamics of herpes simplex virus type 1 (HSV-1) infection of neurons at the single-cell level. We used micrometer-scale Matrigel beads, termed microgels, …
