2012年3月1日 · Human serum transferrin (hTF) is a bilobal glycoprotein that reversibly binds Fe 3+ and delivers it to cells by the process of receptor-mediated endocytosis. Despite decades …

2012年12月19日 · Human serum transferrin (hTF) binds Fe (III) tightly but reversibly and delivers it to cells via a receptor-mediated endocytosis process. The metal-binding and...

As an essential requirement for any functional hTF, both lobes of purified Optiferrin ™ bind Fe 3+ tightly yet reversibly. Although previously shown to be capable of delivering Fe 3+ to cells, the …

Human serum transferrin (hTF) binds Fe(III) tightly but reversibly, and delivers it to cells via a receptor-mediated endocytosis process. The metal-binding and release result in significant …

2014年7月1日 · Human serum transferrin (hTf) is a single-chain bilobal glycoprotein that efficiently delivers iron to mammalian cells by endocytosis via the transferrin/transferrin receptor system.

2012年3月3日 · The recent crystal structure of two monoferric human serum transferrin (Fe N hTF) molecules bound to the soluble portion of the homodimeric transferrin receptor (sTFR) …

Essential to iron homeostasis is the transport of iron by the bilobal protein human serum transferrin (hTF). Each lobe (N- and C-lobe) of hTF forms a deep cleft which binds a single Fe …

2011年6月15日 · 提供了用于确定准确速率常数的一系列生物物理技术的关键评估。一般意义 通过 hTF 将 Fe(3+) 输送到活跃分裂的细胞是必不可少的。Fe(3+) 过多或过少都会直接影响个人的幸 …

Human serum transferrin (hTF) is an 80-kDa bilobal glycoprotein synthesized by hepatocytes and secreted into the serum where it binds iron acquired from the diet (1). Ferric iron (Fe 3+) is …

Human serum transferrin (hTf) is a single-chain bilobal glycoprotein that efficiently delivers iron to mammalian cells by endocytosis via the transferrin/transferrin receptor system. While …