成纤维细胞生长因子 FGF（Fibroblast Growth Factors，FGFs）最初是以其成纤维细胞的有丝分裂能力命名的。 FGF及其受体在动物界高度保守。 在哺乳动物中， FGF家族 包括23种多肽， …

FGF通过与 成纤维细胞生长因子受体 （FGFR）介导的信号轴刺激或维持代谢、组织稳态和发育所需的特定细胞功能，主要调节细胞增殖，分化，存活，迁移和代谢。 哺乳动物FGF家族由22 …

FGF, also known as fibroblast growth factor, represents a family of approximately two dozen heparin-binding proteins that play pivotal roles in numerous cellular processes related to …

成纤维细胞生长因子 (FGF)通过结合并激活靶细胞上的高亲和力 FGF 受体 (FGFR) 来发挥作用，从而导致涉及激酶和转录因子的信号转导级联。 成纤维细胞生长因子激活的信号通路会导致如 …

Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by the macrophages. They are involved in a wide variety of processes, most notably as crucial …

Fibroblast growth factors (Fgfs) and Fgf receptors (Fgfrs) comprise a signaling system that is conserved throughout metazoan evolution. Twenty-two Fgfs and four Fgfrs have been …

FGF ligands are polypeptide growth factors that regulate several developmental processes including cellular proliferation, differentiation, and migration, morphogenesis, and patterning. …

2020年9月2日 · Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR) signaling has crucial roles in a multitude of processes during embryonic …

Here we review the mechanisms of Fgf signaling by focusing on genetic strategies that enable in vivo analysis. These studies support an important role for Erk1/2 as a mediator of Fgf signaling …

Fibroblast Growth Factors (FGFs) are potent regulators of cell proliferation and differentiation. They are critically important in normal development, tissue maintenance, wound repair, and …