HBcAg (core antigen) is a hepatitis B viral protein. [1][2] It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious).

2021年10月29日 · The hepatitis B core antigen (HBcAg) is part of the nucleocapsid within HBV; it is not routinely measured in clinical practice; however, the body produces a corresponding antibody to this antigen called hepatitis B core antibody (anti-HBc), which is clinically relevant.

Hepatitis B Surface Antigen (HBsAg) – The "surface antigen" is a protein found on the surface of the hepatitis B virus that is present in the blood of someone who is infected. If this test is positive or "reactive," then the hepatitis B virus is present.

Hepatitis core antigen (HBcAg) is a protein translated from HBV core ORF and component of HBV nucleocapsid. HBcAg is present intracellularlly and not routinely detectable in the serum of infected individuals. Antibodies to core protein (anti-HBc) are the host's immune response that can be divided into IgM and IgG.

Hepatitis B core-related antigen (HBcrAg) is a novel biomarker that has an important role in chronic hepatitis B (CHB), because it correlates with serum HBV DNA and intrahepatic cccDNA.

HBcAg and hepatitis B e antigen (HBeAg) are translated from a common gene but display different antigenic properties. HBcAg, the nucleocapsid protein, is found in liver tissue in patients with acute or chronic HBV infection.

Antibody to HBcAg (anti-HBc, or HBcAb) usually appears at the onset of clinical illness; thereafter, titers gradually diminish, usually over years or life. Its presence with anti-HBs indicates recovery from previous HBV infection.

2000年12月20日 · HBc antigen (HBcAg) capsids are extremely immunogenic and can activate naive B cells by cross-linking their surface receptors. The molecular basis for the interaction between HBcAg and naive B cells is not known.

2020年7月11日 · Because hepatitis B core antigen (HBcAg) is the most immunogenic component of HBV, high levels of first IgM anti-HBc and then IgG anti-HBc are produced. Anti-HBc, usually determined as total IgM and IgG antibodies, is considered the most sensitive and reliable markers of HBV exposure.

hepatitis B core antigen (HBcAg) a core protein antigen of the hepatitis B virus present inside complete virions (Dane particles) and in the nuclei of infected hepatic cells, indicating the presence of reproducing hepatitis B virus.