For the diagnosis of myocardial infarction. The HBDH is an alternate to determine the LDH isoenzymes (LDH-1). HBDH indirectly measures LDH-1 of heart activity. HBDH is cheaper than the LDH isoenzyme assay. Roasalki and Wilkinson advocated the ratio of LDH/HBDH. In healthy individual serum, the ratio of LDH/HBDH varies from 1.2 to 1.6.

α-hydroxybutyrate dehydrogenase (α-HBDH) is an auxiliary marker of myocardial injury, which was reported to have an increased specificity for detecting myocardial injury, starting to increase 8–12 h after damage, reaching peak serum concentrations after 48–72 h and returning to baseline after 7–14 days (9).

Alpha-hydroxybutyrate dehydrogenase (α-HBDH) is a cardiac enzyme commonly found in the heart, brain, kidneys, and red blood cells (11). Elevated α-HBDH has been reported to be related to myocardial infarction and hepatic damage (12). Recent research has revealed that serum α-HBDH levels have a role in atherothrombotic events (13).

Our study found that serum α‐HBDH is an independent risk factor for in‐hospital mortality and disease severity among COVID‐19 patients. α‐HBDH assessment may aid clinicians in identifying high‐risk individuals among COVID‐19 patients. Keywords: α‐HBDH, Coronavirus disease, Prognosis, Disease progression.

2024年6月26日 · α-Hydroxybutyrate dehydrogenase (α-HBDH) is a myocardial enzyme that utilizes α-ketobutyric acid as a substrate to measure the activity of lactate dehydrogenase (LDH) isoenzymes LDH1 and LDH2 in serum. It is predominantly found in human cardiomyocytes, exhibiting the highest content [8] and serves as one of the biomarkers of myocardial injury.

2019年12月3日 · In the current study, we investigated whether α-hydroxybutyrate dehydrogenase (HBDH) is associated with atherothrombotic events in 83 stable patients undergoing infrainguinal angioplasty and...

Our study found that serum α-HBDH is an independent risk factor for in-hospital mortality and disease severity among COVID-19 patients. α-HBDH assessment may aid clinicians in identifying high-risk individuals among COVID-19 patients.

2024年9月10日 · In our investigation, we examined biochemical parameters and identified hydroxybutyrate dehydrogenase (HBDH) as a significant predictor for diffuse large B cell lymphoma (DLBCL) patients. A group of 100 patients was used to explore potential biomarkers related to progression-free survival (PFS).

2022年10月17日 · Alpha-hydroxybutyrate dehydrogenase (α-HBDH) is a cardiac enzyme commonly found in the heart, brain, kidneys, and red blood cells (11). Elevated α-HBDH has …

2024年4月30日 · α-HBDH is a predictor of the in-hospital mortality and postoperative MACE, guiding admission stratification of patients with AAD. Acute aortic dissection (AAD) is a severe aortic disease with a high morbidity and mortality [1–4].