
Hemoglobin H identification by high-performance liquid …
HPLC chromatograms were reviewed to determine the presence and retention time of the Hb H peak. Results: Hemoglobin H was not reported in 24.2% of patients (23 of 95) with genotypic …
HPLC in Characterization of Hemoglobin Profile in Thalassemia …
High-performance liquid chromatography (HPLC) is a technique introduced for the accurate diagnosis of hemoglobinopathies and thalassemias. The advantage of the HPLC system is the …
HAEMOGLOBIN PATTERN ANALYSIS - Prevention of …
Cation: exchange high performance liquid chromatography (HPLC) has emerged as the method of choice for quantification of HbA 2, HbF and for detection and quantitation of the Hb variants, …
Haemoglobin H (HbH) Disease - LearnHaem | Haematology Made Simple
In HbH disease, a fast band corresponding to haemoglobin H can be observed. HPLC can also identify HbH and Hb Constant Spring. Confirmation of α thalassaemia is best done via genetic …
Role of HPLC in the detection of HbH disease - ResearchGate
2011年4月1日 · Together with a complete blood count, the CE-HPLC is effective in categorizing hemoglobinopathies as traits, homozygous disorders and compound heterozygous disorders. …
The Diagnosis of α-Thalassaemia: A Case of Hemoglobin H −α
We report a case of hemolytic anemia that was subsequently identified to be a case of α-thalassaemia harboring the common rightward 3.7 kb deletion/HbH. The diagnosis was based …
Role of HPLC in the detection of HbH disease - PubMed
Role of HPLC in the detection of HbH disease. Role of HPLC in the detection of HbH disease Indian J Pathol Microbiol. 2011 Apr-Jun;54(2):407. doi: 10.4103/0377-4929.81590. Authors …
From HPLC analysis report, It was observed that 24 out of 97 individuals had HbA2 values in and around the range for Beta thalassemia trait (typically between 4.0% and 6.0%, and is rarely …
Conversely, modern methods such as HPLC provide putative identification and estimation of the fractions in a matter of minutes, allowing a confident diagnosis of high HbA2 β-Thalassemia …
HPLC in Characterization of Hemoglobin Profile in Thalassemia …
2015年3月1日 · High-performance liquid chromatography (HPLC) is a technique introduced for the accurate diagnosis of hemoglobinopathies and thalassemias. The advantage of the...