血红蛋白 H 病 (HbH) 病属于非输血依赖性地中海贫血组。 HbH 疾病通常由三个 α-珠蛋白等位基因失活导致 Hb 的 α-珠蛋白链产生不足，并形成 β-4 四聚体 (HbH)。 HbH四聚体对氧具有高亲 …

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HbH disease is characterised by a moderate anaemia (Hb typically ~80g/L, but can range from 60-100g/L). Haemolytic episodes are triggered by infections, especially parvovirus B19 …

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Individuals with deletional HbH disease usually have mild asymptomatic anaemia that remains unsuspected in many cases until an incidental laboratory finding of anaemia prompts …

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HbH包涵体染色阳性时，在红细胞内出现大小不等、数目不一的墨绿蓝色圆形小体分布不规则，散在于整个红细胞内。 观察孵育1小时后血涂片中 1000个红细胞，报告含有HbH包涵体阳性细 …

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2.血浆：可用EDTA或肝素作为抗凝剂，标本采集后30分钟内于2 - 8° C 1000 x g离心15分钟，或将标本放于-20℃或-80℃保存，但应避免反复冻融。 3.细胞培养物上清或其它生物标本：1000 x …