The discography of the American rock band Heart consists of 15 studio albums, nine live albums, nine compilation albums, 64 singles and 35 music videos. The group, led by Ann and Nancy Wilson , have sold about 35 million records worldwide.

LPS exerts time- and dose-dependent effects on cellular function in H9c2 cells. LPS is known to induce cardiac hypertrophy and apoptosis in the heart. We treated H9c2 cells with LPS at various concentrations for two different exposure times. First, H9c2 cells were incubated with 1, 5, and 10 μg/ml LPS for 3 h.

2024年10月17日 · Heart mass indexed to body mass in the LPS group was significantly higher compared to the control group (P = 0.002). The internal diameter of the LV chamber during both diastole (P = 0.04) and...

2024年9月24日 · LPS pretreatment confers cardiac protection against ISO-induced injury through TLR4 mediated type 1 and 2 interferon signaling, consistent with trained innate immune tolerance.

2017年6月7日 · Our data demonstrate that hiPSC-CMs possess the functional reaction system involved in endotoxin-induced inflammation and can model some bacterium-induced inflammatory responses in cardiac...

2024年2月20日 · In this study, we utilized lipopolysaccharide (LPS) to construct a sepsis rat model and LPS treatment of neonatal rat cardiomyocytes (NRCMs) to explore the mechanism of IP3R2 regulating...

The presented results showed that rutin significantly improved morphological changes of myocardium and relieved cardiac marker enzymes [creatine kinase (CK) and lactate dehydrogenase (LDH)] level to protect heart in LPS-induced sepsis.

Endo-toxin, often referred to as LPS, binds to toll-like receptor 4 (TLR4)/ myeloid differentiation protein 2 (MD2) complexes on various tissues including cells of the innate immune system, smooth muscle and endothelial cells of blood vessels …

1997年12月19日 · We hypothesized that LPS, in clinically relevant levels (1 ng/mL), directly depresses contractility and β-adrenergic responses in cardiac myocytes. Cardiac myocytes were isolated from the left ventricle of adult rabbits using digestive enzymes (collagenase and …

2001年3月16日 · Fluorescently labeled LPS was used to treat primary cardiomyocyte cultures, perfused heart preparations, and the RAW264.7 macrophage cell line. Using confocal microscopy and spectrofluorometry, we found that LPS was rapidly internalized in cardiomyocyte cultures and Langendorff-perfused hearts.