HEK 293 cells have a complex karyotype, exhibiting two or more copies of each chromosome and with a modal chromosome number of 64. They are described as hypotriploid, containing less than three times the number of chromosomes of a haploid human gamete.

293 [HEK-293] is a cell line exhibiting epithelial morphology that was isolated from the kidney of a human embryo. This cell line can be used in industrial biotechnology and toxicology research. It has applications in efficacy testing and viruscide testing.

2021年6月18日 · Human Embryonic Kidney 293 (HEK 293) cells are one of the most frequently used cell lines for biotechnology and research studies. These cells are quite popular because of their distinct properties like fast-growing, robustness, and ease of maintenance and transfection.

2019年1月8日 · Human embryonic kidney 293 (HEK293) cells are one of the most common cell lines used for research purposes. This article examines why they are so popular.

2023年2月6日 · HEK293 cells are Human Embryonic Kidney cells, originally isolated and grown by Dutch biologist Alex Van der Eb in the early 1970s. They were transfected with sheared adenovirus 5 (Ad5) DNA by Frank Graham, a postdoc in Van der Eb’s lab.

2024年11月12日 · HEK293 cells are widely used in the production of adenoviral vectors, adeno-associated viral vectors, protein production, vaccine development, anti-cancer reagents, and cell biology research. Characteristics and Uses of HEK293 Cell Lines.

2015年9月15日 · 293 cell line (widely known as the Human Embryonic Kidney 293 cells) and its derivatives were the most used cells after HeLa in cell biology studies and after CHO in biotechnology as a vehicle for the production of adenoviral vaccines and recombinant proteins, for analysis of the neuronal synapse fo …

Here, we present a genomic and transcriptomic analysis of the HEK293 parental cell line along with five widely used HEK293 derivatives.

Human embryonic kidney 293 (abbreviated HEK 293 or HEK cells) are a cell line that was originally cultured from the kidney cells of a human embryo placed in tissue culture. These cells were transformed with sheared adenovirus DNA in a laboratory in Leiden, the Netherlands.

HEK293 is a cell line derived from human embryonic kidney cells grown in tissue culture. They are also known, more informally, as HEK cells. This particular line was initiated by the transformation and culturing of normal HEK cells with sheared adenovirus 5 DNA.