In the present study, we analyzed the outcome of hematogenous PJIs, which were diagnosed by comprehensive definition criteria, in particular excluding acute exacerbations of chronic postoperative PJI. In addition, the reasons for treatment failure were evaluated and classified as persisting or relapsing vs new infection.

Haematogenous PJI was defined by diagnosis of infection ≥1 month after surgery, acute manifestation after a pain-free period and positive blood or prosthetic-site culture and/or evidence of distant infectious focus consistent with the pathogen.

S. aureus is a frequently isolated pathogen in cases of hematogenous PJI, and several small studies have suggested that S. aureus bacteremia is associated with a 30 to 40% risk of hematogenous seeding of in situ arthroplasties (73 – 75).

Results: We identified 14 patients with acute hematogenous PJI who underwent I&D and polyethylene exchange with retention of metal components. The mean time from primary TAA to symptoms was 43 months (range 1-147 months). The average time from onset of symptoms to I&D and polyethylene exchange was 11.4 ± 5.6 days.

2019年7月1日 · Recognition of infectious origin of haematogenous periprosthetic joint infections (PJI) is crucial. We investigated the primary focus and characteristics of haematogenous PJI. Consecutive patients who presented with haematogenous PJI between 01/2010 and 01/2018 were retrospectively analysed.

We report our experience of the management of acute haematogenous prosthetic joint infection (AHPJI) in patients during a 3-year prospective study in nine Spanish hospitals. Fifty patients, of whom 30 (60%) were female, with a median age of 76 years, were diagnosed with AHPJI.

2018年4月1日 · Major microorganisms isolated in hematogenous PJIs were streptococci and staphylococci. Among streptococci, Streptococcus agalactiae (group B) was the most frequent. This study was undertaken to analyze prosthetic joint infection (PJI)-causing microorganisms and compare their distribution patterns according to PJI classification.

We have confirmed our initial hypotheses that LA-PJI is the most common mode of presentation, likely as a result of acute hematogenous seeding, and that there is substantial heterogeneity in surgical and antibiotic management of PJIs.

2023年10月14日 · Periprosthetic joint infection (PJI) is a unique clinical entity, markedly different from infections involving native bones or joints.[1] PJI is characterized by a complex interplay between microbes, predominantly bacteria but occasionally fungi, and the host immune response.

2021年11月21日 · Late acute hematogenous periprosthetic joint infection (PJI) is a devastating complication that can occur after total knee arthroplasty (TKA). The reported incidence of late acute hematogenous PJI following TKA is 0.5%, 3%, 2%, and …