This topic will review the general principles underlying the therapeutic use of unfractionated and LMW heparins including dosing, monitoring, and reversal of anticoagulation, as well as danaparoid (not available in the United States).

2024年11月25日 · Detailed Heparin dosage information for adults and children. Includes dosages for Prevention of Thromboembolism in Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism and more; plus renal, liver and dialysis adjustments.

Anticoagulation therapy is the main treatment for VTE and must be applied with knowledge and skill in order to achieve the optimal balance between reduction in recurrent VTE and the risk of potentially life-threatening bleeding.

2020年10月2日 · Objective: These evidence-based guidelines from the American Society of Hematology (ASH) intend to support patients, clinicians, and others in decisions about treatment of VTE. Methods: ASH formed a multidisciplinary guideline panel balanced to minimize potential bias from conflicts of interest.

These highlights do not include all the information needed to use HEPARIN SODIUM INJECTION safely and effectively. See full prescribing information for HEPARIN SODIUM INJECTION. † Based on 150...

To provide standardized dosing and monitoring guidelines for patients receiving unfractionated heparin (UFH) therapy.

Unfractionated heparin (UFH) is a mixture of sulfated glycosaminoglycans, some of which possess anticoagulant properties. It is rapidly removed from the body with a half-life of 30 to 60 minutes, however the half-life may increase with increasing dosage or in renal impairment.

2018年11月27日 · Conclusions: Strong recommendations included using patient self-management of international normalized ratio (INR) with home point-of-care INR monitoring for vitamin K antagonist therapy and against using periprocedural low-molecular-weight heparin (LMWH) bridging therapy.

Dosing information: 60 units/kg bolus (maximum 4000 units) followed by an intravenous infusion of 12 units/kg per hour (maximum 1000 units per hour), adjusted to target APTT. On initiation of infusion, check the APTT RATIO after 4 to 6 hours.

Heparin sodium 5000 units intravenously over 5 minutes is the standard loading dose. Higher dose of 10,000 units may be required for severe pulmonary embolism. The prescriber must use the designated loading dose box on the adult intravenous …