Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein is a protein that in humans is encoded by the HERPUD1 gene. [5][6][7] The accumulation of …

2024年12月25日 · HERPUD1 (Homocysteine Inducible ER Protein With Ubiquitin Like Domain 1) is a Protein Coding gene. Diseases associated with HERPUD1 include Hereditary Breast …

2015年2月27日 · Herpud1 is an ER-localized protein that contributes to endoplasmic reticulum (ER) homeostasis by participating in the ER-associated protein degradation pathway. The Nrf1 …

2025年2月8日 · Herpud1 deficiency alleviates homocysteine-induced aortic valve calcification. The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development …

Gene Ontology (GO) 和 Kyoto Encyclopedia of Genes and Genomes pathways (KEGG) 分析表明，HERPUD1 及其相关基因富含调节免疫、内质网应激、泛素依赖性降解、ERS 诱导的细胞凋 …

HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways. The Brucella effector BspL targets …

未折叠蛋白在内质网 (ER) 中的积累会触发 ER 应激反应。 这种反应包括抑制翻译以防止未折叠蛋白质的进一步积累、参与多肽折叠的蛋白质表达增加，称为未折叠蛋白质反应 (UPR) ，以及 …

2022年12月21日 · HERPUD1 is an important early marker of endoplasmic reticulum stress (ERS) and is involved in the ubiquitination and degradation of several unfolded proteins. However, its …

Homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 1 (HERPUD1), an ER resident protein, is upregulated in response to ER stress and …

2022年12月22日 · HERPUD1 is an important early marker of endoplasmic reticulum stress (ERS) and is involved in the ubiquitination and degradation of several unfolded proteins. However, its …