2013年11月1日 · One of the most important links in the chain of the avian host’s immune response to pathogens and an integral part of the avian innate defenses is the heterophil. This granulocytic white blood cell, a counterpart to the mammalian neutrophil, is the first line of defense against invasive pathogens.

2016年8月26日 · The heterophil is the predominant leukocyte in health in many avian species and predominates in many disease conditions (Figure 49-1). It has a lobulated, condensed nucleus, although the degree of lobulation is less than that of mammals.

The heterophil (SEE FIGURE) is the avian equivalent of the mammalian neutrophil, and the function of the two cell types is thought to be similar. In many avian species, the heterophil is the most common WBC seen.

This review examines the avian heterophil leucocyte and provides a morphological and cytochemical profile drawn from light and electron microscopy studies of these cells and their characteristic cytoplasmic granules.

The major differences between mammalian and avian hematology include the presence of nucleated erythrocytes, thrombocytes, and heterophil granulocytes in the blood of birds. Reading the slide provides the opportunity to determine the differential leukocyte count which is a key component in calculating the total white blood cell count.

Heterophils are specialized white blood cells which are primary components of innate immunity. Considered the avian equivalent to mammalian neutrophils, heterophils respond to similar microbial stimuli, exhibit chemotaxis, phagocytize microbial pathogens, and produce cytokines and metabolites to maintain immune homeostasis.

2022年11月7日 · Avian erythrocytes have, on average, a shorter half-life than mammalian erythrocytes, so some polychromasia from circulating immature red blood cells is considered normal (Campbell and Ellis, 2007). Avian leucocytes are similar to mammalian lines except in the fact that avian heterophils are equivalent to mammalian neutrophils (Campbell and ...

Avian thrombocytes are involved in blood clotting, and also have a phagocytic function, but are not directly involved in the initiation of blood clotting as are mammalian platelets. Avian thrombocytes contain large quantities of 5‐hydroxytryptamine (serotonin) and acid‐phosphatase,

avian blood films. Leukocytes The granulocytes in the blood film of birds vary in appear-ance but can be classified as heterophils, eosinophils, and basophils. The avian heterophil is functionally equivalent to the mammalian neutrophil, and is the most abun-dant granulocyte of many species of birds. The nucleus

1998年7月1日 · The avian heterophil lacks myeloperoxidase and depends primarily on nonoxidative mechanisms for antimicrobial activity. The beta-defensins found in heterophil granules can kill a wide variety of bacterial pathogens and are a major component of the heterophil antimicrobial arsenal.