2024年12月25日 · HGF (Hepatocyte Growth Factor) is a Protein Coding gene. Diseases associated with HGF include Deafness, Autosomal Recessive 39 and Rare Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and MIF Mediated Glucocorticoid Regulation.

Hepatocyte Growth Factor (HGF) is a cytokine and marker of cardiovascular disease (CVD) risk. Less is known about HGF and incident heart failure (HF). We examined the association of HGF with incident HF and its subtypes in a multi-ethnic cohort.

2021年12月2日 · Hepatocyte growth factor (HGF), also known as scatter factor, is a multi-functional cytokine that was originally cloned as a potent mitogen for hepatocytes in primary cultures (1) and was later identified as a cell motility factor for …

In this study, a label-free quantitative proteomic approach was used to determine the effect of the high-fat diet on the proteomics profile of liver tissue and to identify novel NAFLD related TFs. Mice were fed with HFD for 16 weeks to establish a NAFLD mouse model. Mice fed with normal chow diet were taken as controls.

Hepatoma-derived growth factor (HDGF) 1 is the first member of the HDGF family of proteins that contain a well-conserved N-terminal amino acid sequence which we call the hath (h omologous to a mino t erminus of H DGF) region (1,2).HDGF was purified from the conditioned medium of human hepatoma-derived HuH-7 cells, which proliferate autonomously in a serum-free chemically defined medium, and ...

Hepatocyte Growth Factor (HGF) is a multipotent cytokine that stimulates cell proliferation, differentiation, motility and invasiveness. At the tissue level, HGF induces angiogenesis, hematopoiesis, chondrogenesis and also supports organogenesis. HGF is a natural ligand for the c-Met proto-oncogene product of receptor tyrosine kinase.

Hepatocyte growth factor/scatter factor (HGF/SF) stimulates cell proliferation, motility, and morphogenesis by activation of its receptor, the c-Met tyrosine kinase. HGF/SF is structurally related to plasminogen, including an amino-terminal hairpin loop, four kringle domains, and a serine protease-like region.

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2021年8月7日 · Hepatocyte growth factor (HGF) has been studied as a protective factor for the survival of islet β cells and regulatory glucose transport and metabolism in many studies. The addition of exogenous HGF to cells or mice is the most common way to study HGF, but the persistence and stability of the administered HGF are unclear.