
HFTH | Human Factors Transforming Healthcare
Human Factors Transforming Healthcare (HFTH) was founded by embedded human factors practitioners. The goal of HFTH is to provide resources for HF practitioners, providers, and hospitals looking to successfully apply HF principles in their organizations.
通过使用基因工程人类铁蛋白纳米粒子上呈现的多个肿瘤受体结合 …
人类铁蛋白重链纳米颗粒(hFTH)经过基因工程改造,可在其表面呈现肿瘤受体结合肽(亲和力和/或RGD衍生的环状肽,在此处称为4CRGD)。 亲和体和4CRGD分别与人表皮生长因子受体I(EGFR)和人整联蛋白αvβ3特异性结合并牢固结合,它们在各种肿瘤细胞上均过表达。 通过体外培养EGFR过表达的腺癌(MDA‐MB‐468)和整联蛋白过表达的胶质母细胞瘤细胞(U87MG),可以明确肿瘤细胞上的受体与工程hFTH上的受体结合肽之间的特异性相互作用 …
Human Factors Transforming Healthcare | LinkedIn
Enhancing healthcare practices through applied and embedded human factors | We envision a healthcare system where human factors principles are embedded in every aspect of patient care, ensuring...
纳米粒子对癌细胞的肽配体介导的内吞作用:细胞受体结合肽与细 …
使用肽配体-人铁蛋白重链(hFTH)纳米粒子的常见载体,分析和比较了两种类型的肽配体(细胞受体结合肽(CRBP)和细胞膜穿透肽(CMPP))的内吞作用介导性能。 二十四份CMPP(人类免疫缺陷病毒衍生的TAT肽)和/或CRBP(对人整联蛋白(αvβ3)或表皮生长因子受体I(EGFR)具有强特异性亲和力的肽配体)在每个hFTH纳米微粒的表面上遗传呈现了各种癌细胞)。 在过表达整联蛋白和EGFR的癌症和人类皮肤成纤维细胞(对照)的体外培养物中,估计 …
Student Resources | Human Factors Transforming Healthcare
The mission of the Student Advisory Board is to introduce human factors and ergonomics students to the world of embedded healthcare through virtual and in-person learning sessions and networking opportunities.
Enhanced In Vivo Tumor Detection by Active Tumor Cell Targeting …
2016年6月30日 · Human ferritin heavy-chain nanoparticle (hFTH) is genetically engineered to present tumor receptor-binding peptides (affibody and/or RGD-derived cyclic peptides, named 4CRGD here) on its surface. The affibody and 4CRGD specifically and strongly binds to human epidermal growth factor receptor I (EGFR) and human integrin αvβ3, respectively ...
Ferritin heavy chain as a molecular imaging reporter gene in …
Our study illustrated that hFTH generated cellular MR imaging contrast efficiently in glioma via regulating the expression of transferritin receptor. This might be a useful reporter gene in cell tracking and MR molecular imaging for glioma diagnosis, gene therapy and tumor metastasis.
Bimodal lentiviral vector encoding myc-tagged human ferritin …
The bimodal lentiviral vector encoding myc-tagged human ferritin heavy chain (myc-hFTH) and green fluorescent protein (GFP), abbreviated as Lenti-myc-hFTH, was constructed by Kim et al. for use in cell tracking studies with magnetic resonance imaging (MRI) and optical imaging (1).
In vitro characterization of human ferritin heavy chain.
We tested human ferritin heavy chain (hFTH) as a reporter gene for in vivo tracking of stem cells by cardiac MRI. Swine cardiac stem/progenitor cells were transduced with a lentiviral vector to...
About HFTH | About Human Factors Transforming Healthcare
Human Factors Transforming Healthcare (HFTH) was founded by embedded human factors practitioners. The goal of HFTH is to provide resources for HF practitioners, providers, and hospitals looking to successfully apply HF principles in their organizations.