Hemoglobin A2 (HbA 2) is a normal variant of hemoglobin A that consists of two alpha and two delta chains (α 2 δ 2) and is found at low levels in normal human blood. Hemoglobin A2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene.

Elevated levels of Hemoglobin A2 (HbA2) in a blood test can indicate certain health conditions, most notably beta thalassemia, a blood disorder. Hemoglobin is a protein in your red blood cells that carries oxygen throughout your body.

2022年2月11日 · Healthcare providers typically test for the four common hemoglobin types: Hemoglobin Types A11 and A2 (HgbA1 and A2): Hemoglobin A11 accounts for most of the hemoglobin in your normal red blood cells. Hemoglobin A2 accounts for about 2% to 3 % of your total hemoglobin.

Hemoglobin A 2 levels have special application to the diagnosis of β-thalassemia trait, which may be present even though peripheral blood smear is normal. (This reflects the underlying genetic spectrum of β-thalassemia, which in reality is a complex of 20 to 30 distinct conditions.)

Hemoglobin (Hb) A 2 (α 2 δ 2) constitutes less than 3% of the total hemoglobin (Hb) in adults and has almost no physiological importance. 1 On the other hand, the determination of Hb A 2 is an important tool to diagnose the beta-thalassemia trait (BTT). 1, 2 Although individuals with BTT do not need treatment, the accurate detection of the carri...

2024年3月29日 · Learn why you may need an Hgb test, what the typical ranges are for Hgb, and what can cause abnormal Hgb levels. What is a healthy hemoglobin level by age? Your age and gender both affect your...

Red blood cell hemoglobin is used to transport oxygen from the lungs to the tissues. Normal adult hemoglobin contains 95% to 98% hemoglobin A (two alpha chains and two beta chains). It also contains 2% to 3% Hb A2 (normal variant with two alpha chains and two delta chains) and 1% to 2% fetal hemoglobin consisting of two alpha and two gamma chains.

Optimal Result: 1.8 - 3.2 %. Interpret Your Laboratory Results Now. Hemoglobin A2 makes up about 2%-3% of Hb in adults; it has two alpha and two delta protein chains. Your medical lab tests hold vital information about your health. Our tools help …

HbA2, composing of two α chains and two δ chains, is a minor component of the hemoglobin present in normal adult red blood cells, accounting for about 2.5% of the total hemoglobin in healthy individuals. However, HbA2 level is also elevated in some pregnant women.

Hemoglobin A2' (delta 16 Gly → Arg) is globally the commonest delta chain variant of HbA2. It is clinically and hematologically silent but its sole importance lies in the underestimation of HbA2 quantity during the workup of β-thalassaemia trait.