
Conformational Landscapes of Halohydrin Dehalogenases and …
2020年12月1日 · Halohydrin dehalogenases (HHDH) are industrially relevant biocatalysts exhibiting a promiscuous epoxide-ring opening reactivity in the presence of small nucleophiles, …
狹道英雄-官網首頁-Hero:Dark Haze
海柔爾是一名正義的女騎士,出生在王國下城區的貧民窟裡。 因為出身她備受針對,但她總能憑藉功績屢屢升遷,最終成為了無可爭議的遠征軍二把手。 簡介: “我在此見證、記錄。 盧卡原是 …
Properties and biotechnological applications of halohydrin ...
2012年11月1日 · Halohydrin dehalogenases (HHDHs) are lyases that catalyze the cleavage of carbon–halogen bond of halohydrins. They also can catalyze the reverse reaction in the …
Recent advances on halohydrin dehalogenases—from enzyme
2016年8月8日 · These enzymes, also called halohydrin dehalogenases (HHDHs), haloalcohol dehalogenases, or halohydrin hydrogen-halide-lyases, belong to the enzyme class of lyases …
Intact-cell detection of halohydrin dehalogenase activity and ...
2024年11月1日 · Halohydrin dehalogenase (HHDH) can degrade 1,2,3-trichloropropanol and other halogenated alcohols. These enzymes exhibit stereoselectivity and can be used to …
Significant improvement of the enantioselectivity of a …
Halohydrin dehalogenases (HHDHs) have attracted much attention due to their ability to synthesize enantiomerically enriched epoxides and β-haloalcohols. However, most of the …
Enhancing the biocatalytic manufacture of the key intermediate of ...
2017年2月6日 · Halohydrin dehalogenases (HHDHs, EC 4.5.1.X), also known as halohydrin epoxidases or halohydrin hydrogen-halide-lyases, are microbial enzymes that catalyze the …
Rational design of halohydrin dehalogenase for efficient chiral ...
2020年9月15日 · Halohydrin dehalogenase (EC4.5.1.X, HHDH) is one of the key enzymes catalyzing the reversible dehalogenation of β-haloalcohols with the formation of epoxide. It is …
Insights into the molecular determinants of thermal stability in ...
Halohydrin dehalogenases (HHDHs) are promising enzymes for application in biocatalysis due to their promiscuous epoxide ring-opening activity with various anionic nucleophiles. So far, …
Covalent immobilization of halohydrin dehalogenase for efficient ...
2022年2月18日 · Halohydrin dehalogenase (HHDH)-mediated dehalogenation of 1,3-dichloro-2-propanol (1,3-DCP) is a key step in the chemoenzymatic synthesis of epichlorohydrin (ECH) …
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